Showing papers by "Daniel Maspoch published in 2010"
TL;DR: In vitro cancer cell cytotoxicity assays showed that these capsules readily release doxorubicin, which shows anticancer efficacy, which open up new avenues for metal-organic capsules to be used as potential drug delivery systems.
217 citations
TL;DR: This work was supported by projects MAT2009-13977-C03, Nanomateria-DGA, and PI091/08, and funding from the European Network of Excellence MAGMANet is also acknowledged.
Abstract: This work was supported by projects MAT2009-13977-C03, Nanomateria-DGA, and PI091/08. D.M. thanks the Ministerio de Ciencia y Tecnologia
for a RyC contract. A. L. thanks ARAID for financial support. R. de M. is indebted to MICINN for receiving a predoctoral FPU fellowship. Funding from the European Network of Excellence MAGMANet is also acknowledged.
49 citations
TL;DR: It is demonstrated how the protein shell of ferritins can be removed by a simple heat-treatment process while maintaining the encapsulated inorganic nanoparticle intact on the same location of the nanoarray.
Abstract: In this manuscript we demonstrate the spatially controlled immobilization of ferritin proteins by directly writing them on a wide range of substrates of technological interest. Optical and fluorescence microscopy, AFM and TOF-SIMS studies confirm the successful deposition of the protein on those surfaces. Control on nanostructure shape and size, by miniaturizing the dot-like features down to a 100 nm, demonstrates the particular capabilities of the DPN approach. Ultimately, this study gives the opportunity to design nanoparticle-based arrays regarding the growing interest in the use of nanoparticles as structural and functional elements for fabricating nanodevices. Herein, we demonstrate how the protein shell of ferritins can be removed by a simple heat-treatment process while maintaining the encapsulated inorganic nanoparticle intact on the same location of the nanoarray. As a result, this study establishes how direct-write DPN approach could give the opportunity to design not only protein-based nanoarrays but also nanoparticle-based nanoarrays with high-resolution and control.
20 citations
TL;DR: The synthesis, crystal structures, and magnetic properties of two new metal-radical chains built up from a new class of organic radical-based ligands, the polychlorinated triphenylmethyl (PTM) radicals, are reported.
Abstract: We report the synthesis, crystal structures, and magnetic properties of two new metal-radical chains built up from a new class of organic radical-based ligands, the polychlorinated triphenylmethyl (PTM) radicals. Crystal structures of two new 1D coordination polymers, [Cu(2)(PTMDC)(2)(py)(5)(EtOH)].3EtOH (1) and [Co(2)(PTMDC)(2)(DMF)(2)(H(2)O)(6)].5DMF (2) (where PTMDC is a PTM radical functionalized with two carboxylic groups), show similar chain-like structures, in which each of the PTMDC radicals are connecting two Cu(II) or Co(II) metal ions. Therefore, from a magnetic point of view, both structures describe a magnetic chain model based on the PTMDC-M(II) unit. In this manuscript, the magnetic exchange coupling constants between both metal ions and the bridging PTM radicals have been determined. In both cases, the temperature dependence of the magnetic susceptibility reveals antiferromagnetic exchange coupling constants between the PTMDC radicals and Cu(II) (J/k(B) = -42 K) and Co(II) (J/k(B) = -14.6 K) ions based on the exchange Hamiltonian H = -J sum S(A(i))S(A(i+1)).
11 citations