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Daoliang Xu
Researcher at Wenzhou Medical College
Publications - 15
Citations - 514
Daoliang Xu is an academic researcher from Wenzhou Medical College. The author has contributed to research in topics: Proinflammatory cytokine & Protein kinase B. The author has an hindex of 7, co-authored 15 publications receiving 297 citations.
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Metformin protects against apoptosis and senescence in nucleus pulposus cells and ameliorates disc degeneration in vivo.
Deheng Chen,Xia Dongdong,Xia Dongdong,Zongyou Pan,Daoliang Xu,Yifei Zhou,Yaosen Wu,Ningyu Cai,Qian Tang,Chenggui Wang,Meijun Yan,Jing Jie Zhang,Kailiang Zhou,Quan Wang,Yongzeng Feng,Xiang-Yang Wang,Huazi Xu,Xiaolei Zhang,Naifeng Tian +18 more
TL;DR: It is shown that metformin could protect nucleus pulposus cells against apoptosis and senescence via autophagy stimulation and ameliorate disc degeneration in vivo, revealing its potential to be a therapeutic agent for IDD.
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Hydrogen sulfide protects against endoplasmic reticulum stress and mitochondrial injury in nucleus pulposus cells and ameliorates intervertebral disc degeneration
Daoliang Xu,Haiming Jin,Jianxia Wen,Jiaoxiang Chen,Deheng Chen,Ningyu Cai,Yong-Li Wang,Jianle Wang,Yu Chen,Xiaolei Zhang,Xiang-Yang Wang +10 more
TL;DR: The results suggest that H2S plays a protective role in IVDD and the underlying mechanism involves PI3K/Akt and ERK1/2 signaling pathways‐mediated suppression of ER stress and mitochondrial dysfunction in IL‐1&bgr;‐induced NP cells.
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Melatonin ameliorates intervertebral disc degeneration via the potential mechanisms of mitophagy induction and apoptosis inhibition.
Yu Chen,Yanqing Wu,Hongxue Shi,Jianle Wang,Zengming Zheng,Jian Chen,Xi-Bang Chen,Zengjie Zhang,Daoliang Xu,Xiang-Yang Wang,Jian Xiao +10 more
TL;DR: It is suggested that melatonin protected NP cells against apoptosis via mitophagy induction and ameliorated disc degeneration, providing the potential therapy for IDD.
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SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis.
Jianle Wang,Ke Wang,Chongan Huang,Dongdong Lin,Yifei Zhou,Yaosen Wu,Naifeng Tian,Pei Fan,Xiangxiang Pan,Daoliang Xu,Jianing Hu,Ying Zhou,Xiang-Yang Wang,Xiaolei Zhang +13 more
TL;DR: It is demonstrated that DHM might activate SIRT3 to protect rat chondrocytes from TNF-α-induced degeneration and protective effects of DHM on mitochondrial homeostasis in chond rocytes attributed to enhanced Sirt3.
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Risk factors of kyphosis recurrence after implant removal in thoracolumbar burst fractures following posterior short-segment fixation.
Jiaoxiang Chen,Daoliang Xu,Sun-Ren Sheng,Amit Goswami,Jun Xuan,Haiming Jin,Jian Chen,Yu Chen,Zengming Zheng,Xi-Bang Chen,Xiang-Yang Wang +10 more
TL;DR: The loss of correction at follow-up after implant removal was associated with age, A/P ratio and anterior vertebral height, and short-segment pedicle instrumentation including the fractured vertebra was effective in treating thoracolumbar burst fractures.