Darko Kontrec

TL;DR: The addition of water to the system did not induce the tautomeric conversion of the existing form constituted of the ketoamino hydrazide part and the enolimino aldehyde part, but it was involved in the formation of hydrated molecules.

TL;DR: Structural forms of aroylhydrazones derived from nicotinic acid hydrazide have been studied in the solid state by FT-IR spectroscopy and in solution by NMR, UV-Vis and ATR spectroscope to imply tautomeric interconversion was most likely followed by E/Z isomerisation.

TL;DR: Among hydrazones studied, the chloro- and methoxy-derivatives have shown pH dependent and reversible fluorescence emission connected to deprotonation/protonation of salicylidene part of the molecules.

TL;DR: In this article, the origin behind enantioselective cyclization of the biradical intermediate was given by density functional calculations and the very high enantiomeric excess in this type of photocyclization established it as a new method for the enanti-lective synthesis of different large aza-heterocycles.

TL;DR: The obtained results allow assessing the structure–activity relationship of the compounds and provide insight into the further development of this group of aroylhydrazones as more potent and selective anti-neoplastic agents.