D
David A. White
Researcher at University of Nottingham
Publications - 48
Citations - 1091
David A. White is an academic researcher from University of Nottingham. The author has contributed to research in topics: Cholesterol & Cyclandelate. The author has an hindex of 17, co-authored 48 publications receiving 1074 citations.
Papers
More filters
Journal ArticleDOI
The inhibition of the oxidation of low density lipoprotein by (+)-catechin, a naturally occurring flavonoid.
TL;DR: (+)-Catechin inhibited the copper-catalysed oxidation of human low density lipoprotein (LDL) in a dose-dependent manner with complete inhibition at 20 micrograms/mL and appeared to inhibit the uptake and degradation by macrophages of cell-modified LDL.
Journal ArticleDOI
The assembly of triacylglycerol-rich lipoproteins: an essential role for the microsomal triacylglycerol transfer protein.
TL;DR: Current knowledge of the role of MTP in the assembly and secretion of triacylglycerol-rich lipoproteins, and the regulation of its activity in both animal and cell systems are summarized.
Journal ArticleDOI
Inhibition of hepatic cholesterol synthesis and S-3-hydroxy-3-methylglutaryl-CoA reductase by mono and bicyclic monoterpenes administered in vivo.
TL;DR: The ability of a variety of mono- and bicyclic monoterpenes to inhibit hepatic HMGCoA reductase measured 17 hr after in vivo administration to rats was determined, indicating that the effect was specific rather than due to generalized hepatoxicity.
Journal ArticleDOI
The effect of different dietary fatty acids on lipoprotein metabolism: concentration-dependent effects of diets enriched in oleic, myristic, palmitic and stearic acids
Andrew M. Salter,E H Mangiapane,Andrew J. Bennett,Jennifer S. Bruce,Michael A. Billett,K Anderton,Christine B. Marenah,N Lawson,David A. White +8 more
TL;DR: On a low-cholesterol diet, increasing the absolute amount of dietary palmitic acid increases LDL-ch cholesterol more than either myristic or stearic acid, suggesting effects on lipoprotein metabolism may be exerted through specific modulation of the expression of the LDL receptor and apolipoprotein B genes.
Journal ArticleDOI
The role of microsomal triglyceride transfer protein and dietary cholesterol in chylomicron production in diabetes.
A. Gleeson,K Anderton,Daphne Owens,Andrew J. Bennett,Patrick Collins,Alan H. Johnson,David A. White,G. H. Tomkin +7 more
TL;DR: The study shows that microsomal triglycerol transfer protein mRNA is raised in diabetes without an increase in apolipoprotein B48 in the lymph suggesting that micromolecular triglyceride transfer protein regulates chylomicron triglyceride content but not particle number.