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David Brosh

Researcher at Rabin Medical Center

Publications -  45
Citations -  3068

David Brosh is an academic researcher from Rabin Medical Center. The author has contributed to research in topics: Percutaneous coronary intervention & Myocardial infarction. The author has an hindex of 23, co-authored 45 publications receiving 2980 citations. Previous affiliations of David Brosh include Tel Aviv University.

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Main Risk Factors for Nephropathy in Type 2 Diabetes Mellitus Are Plasma Cholesterol Levels, Mean Blood Pressure, and Hyperglycemia

TL;DR: The combination of blood pressure values in the high-normal range with moderately elevated levels of total cholesterol and hemoglobin A1c defines a high-risk group for the progression to diabetic nephropathy and for clinical events related to arteriosclerotic cardiovascular disease.
Journal Article

Use of Enalapril To Attenuate Decline in Renal Function in Normotensive, Normoalbuminuric Patients with Type 2 Diabetes Mellitus

TL;DR: A randomized, double-blind, placebo-controlled trial of the effect of ACE inhibition on the course of nephropathy in 156 patients with type 2 diabetes, who had normal blood pressure and normal urinary albumin excretion at baseline and who attended one of eight clinics in the greater Tel-Aviv area.
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Use of enalapril to attenuate decline in renal function in normotensive, normoalbuminuric patients with type 2 diabetes mellitus. A randomized, controlled trial.

TL;DR: In this paper, the authors evaluated the effect of prolonged ACE inhibition on renal function and albuminuria in patients with type 2 diabetes and found that enalapril treatment resulted in an absolute risk reduction of 12.5% (95% CI, 2% to 23%; P = 0.042) for development of microalbuminuria.
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Effect of no-reflow during primary percutaneous coronary intervention for acute myocardial infarction on six-month mortality.

TL;DR: The association of no-reflow with longer ischemic time and worse initial TIMI flow may indicate the presence of highly organized thrombus burden with higher propensity for distal embolization.