Dávid Fazekas

TL;DR: With SignaLink 2 as a single resource, users can effectively analyze signaling pathways, scaffold proteins, modifier enzymes, transcription factors and miRNAs that are important in the regulation of signaling processes.

TL;DR: A systems‐level resource for NRF2 interactome and regulome that includes 289 protein–protein, 7469 TF–DNA and 85 miRNA interactions is presented and the uncovered regulatory loops may facilitate the development of efficient,NRF2‐based therapeutic agents.

TL;DR: ComPPI as mentioned in this paper is a cellular compartment-specific database of proteins and their interactions enabling an extensive, compartmentalized protein-protein interaction network analysis, which enables the user to filter biologically unlikely interactions, where the two interacting proteins have no common subcellular localizations and to predict novel properties.

TL;DR: Due to its novel features, ComPPI is useful for the analysis of experimental results in biochemistry and molecular biology, as well as for proteome-wide studies in bioinformatics and network science helping cellular biology, medicine and drug design.

TL;DR: SignaLink, a database containing eight major signaling pathways from Caenorhabditis elegans, Drosophila melanogaster and humans, is presented, providing a novel resource for comparative and cross-talk analyses of signaling pathways.