D
David Hellinga
Researcher at MedStar Washington Hospital Center
Publications - 34
Citations - 1087
David Hellinga is an academic researcher from MedStar Washington Hospital Center. The author has contributed to research in topics: Stent & Restenosis. The author has an hindex of 15, co-authored 31 publications receiving 1028 citations.
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Journal ArticleDOI
Safety and efficacy of bioabsorbable magnesium alloy stents in porcine coronary arteries.
Ron Waksman,Rajbabu Pakala,Pramod K. Kuchulakanti,Richard Baffour,David Hellinga,Rufus Seabron,Fermin O. Tio,Eric Wittchow,Sonja Hartwig,Claus Harder,Roland Rohde,Bernd Heublein,Arnim Andreae,Karl-Heinz Waldmann,Axel Haverich +14 more
TL;DR: Quantitative coronary analysis indicates that percentage area stenosis and percentage diameter stenosis in magnesium alloy stent segments improved significantly at 3 months as compared to 28 days; however, reduced neointima did not result in larger lumen.
Journal ArticleDOI
Short-term effects of biocorrodible iron stents in porcine coronary arteries.
TL;DR: The current study demonstrates that stents made of biocorrodible iron are safe and in some of the measured parameters, such as intimal thickness, intimal area, and percentage occlusion, there was a trend in favor of the iron stents.
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PhotoPoint Photodynamic Therapy Promotes Stabilization of Atherosclerotic Plaques and Inhibits Plaque Progression
Ron Waksman,Pauline McEwan,Travis I. Moore,Rajbabu Pakala,Frank D. Kolodgie,David Hellinga,Rufus Seabron,Steven J. Rychnovsky,Jeffrey A. Vasek,Rob Scott,Renu Virmani +10 more
TL;DR: Photodynamic therapy simultaneously reduces plaque inflammation and promotes repopulation of plaques with a SMC-rich stable plaque cell phenotype while reducing disease progression, suggesting that PDT is a promising therapy for the treatment of acute coronary syndromes.
Journal ArticleDOI
Optical coherence tomography and intravascular ultrasound imaging of bioabsorbable magnesium stent degradation in porcine coronary arteries
Tina L. Pinto Slottow,Rajbabu Pakala,Teruo Okabe,David Hellinga,Rachel J. Lovec,Fermin O. Tio,Anh B. Bui,Ron Waksman +7 more
TL;DR: Magnesium-based AMS degrade over a 3-month time period in a porcine model, which is not apparent by angiography but is well-visualized by OCT and IVUS.
Journal ArticleDOI
Oral rapamycin inhibits growth of atherosclerotic plaque in apoE knock-out mice
Ron Waksman,Rajbabu Pakala,Mary Susan Burnett,Cindy P. Gulick,Laurent Leborgne,Jana Fournadjiev,Roswitha Wolfram,David Hellinga +7 more
TL;DR: Oral rapamycin is effective in attenuating the progression of atherosclerotic plaque in the mice and appears to reduce neointima formation when coated on stents.