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David J. Diehl
Researcher at University of Pittsburgh
Publications - 10
Citations - 713
David J. Diehl is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Neurotransmitter & Fenfluramine. The author has an hindex of 6, co-authored 10 publications receiving 702 citations.
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Demonstration in vivo of reduced serotonin responsivity in the brain of untreated depressed patients.
TL;DR: This study provides the first direct visualization of blunted regional brain responses to serotonin release in the brain of patients with major depression, a finding that supports the hypothesis of impaired serotonergic transmission in depression.
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Regional Brain Activity Changes Associated with Fentanyl Analgesia Elucidated by Positron Emission Tomography
Lauri J. Adler,Ferenc E. Gyulai,David J. Diehl,Mark A. Mintun,Peter M. Winter,Leonard L. Firestone +5 more
TL;DR: Data indicate that fentanyl analgesia involves augmentation of painevoked cerebral responses in certain areas, as well as both activation and inhibition in other brain regions unresponsive to pain stimulation alone.
Journal ArticleDOI
The role of dopamine in mood disorders.
David J. Diehl,Samuel Gershon +1 more
TL;DR: The considerable preclinical and clinical evidence supporting the hypothesis that decreased dopamine activity is involved in depression, while increased dopamine function contributes to mania is reviewed.
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Positron emission tomographic imaging of serotonin activation effects on prefrontal cortex in healthy volunteers.
TL;DR: The positron emission tomography 18F-fluorodeoxyglucose (18FDG) method is used to examine the fenfluramine-induced changes in regional cerebral glucose metabolism (rCMRglu) to study abnormalities of serotonin function in the prefrontal cortex.
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Functional neuroanatomy of verbal free recall: A replication study.
James T. Becker,Mark A. Mintun,David J. Diehl,Jeffrey Dobkin,Adam Martidis,David C. Madoff,Steven T. DeKosky +6 more
TL;DR: These data, obtained using a within‐subject design, extend previously reported findings that used mixed within‐and between‐subject designs and demonstrate important functional components of normal auditoryverbal short‐term memory.