D
David Montaigne
Researcher at university of lille
Publications - 120
Citations - 3158
David Montaigne is an academic researcher from university of lille. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 25, co-authored 95 publications receiving 2250 citations. Previous affiliations of David Montaigne include Centre Hospitalier Regional et Universitaire de Lille & Lille University of Science and Technology.
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Journal ArticleDOI
Comment on Patel et al. ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity. Diabetes 2016;65:85-95.
TL;DR: The authors read with interest, but concern, the recently published article, which focused on potential links between angiotensin-converting enzyme 2 (ACE2) deficiency, epicardial adipose tissue (EAT) inflammation, and cardiac dysfunction in a high-fat diet mouse model.
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Right ventricular pacing with mechanical dyssynchrony causes apoptosis interruptus and calcium mishandling.
Didier Klug,Stéphane Boulé,Ludivine Wissocque,David Montaigne,Xavier Marechal,Sidi Mohamed Hassoun,Remi Neviere +6 more
TL;DR: In this article, a pacemaker was inserted into the right jugular vein and positioned either in the right atrium or at the right ventricular (RV) apex for 3 weeks to test whether ventricular dyssynchrony would elicit myocardial alterations in LV calcium handling regulation.
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The synthetic pentasaccharide fondaparinux prevents coronary microvascular injury and myocardial dysfunction in the ischemic heart.
David Montaigne,Xavier Marechal,Steve Lancel,Brigitte Decoster,Philippe Asseman,Remi Neviere +5 more
TL;DR: It is demonstrated that fondaparinux can attenuate inflammatory responses and oxidative stress in connection with IR heart injury and could represent a potential therapeutic strategy for the prevention of myocardial dysfunction.
Basic Research Right Ventricular Pacing With Mechanical Dyssynchrony Causes Apoptosis Interruptus and Calcium Mishandling
Didier Klug,Stéphane Boulé,Ludivine Wissocque,David Montaigne,Xavier Marechal,Sidi Mohamed Hassoun,Remi Neviere +6 more
TL;DR: Slow rate RV pacing causes mechanical dyssynchrony and profound LV alterations in both apoptotic pathways and calcium handling in the early stages of pacing-induced cardiomyopathy.
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Differential effects of inhibitory G protein isoforms on G protein-gated inwardly rectifying K+ currents in adult murine atria.
TL;DR: It is found that mice with deletion of Gαi2 had increased basal and agonist-activated currents, particularly in the right atria while in contrast those with G αi1/Gαi3 deletion had reduced currents.