D
David Sinning
Researcher at Charité
Publications - 25
Citations - 449
David Sinning is an academic researcher from Charité. The author has contributed to research in topics: PCSK9 & Medicine. The author has an hindex of 8, co-authored 21 publications receiving 373 citations.
Papers
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Journal ArticleDOI
European Society of Cardiology/European Atherosclerosis Society Task Force consensus statement on proprotein convertase subtilisin/kexin type 9 inhibitors: practical guidance for use in patients at very high cardiovascular risk.
Ulf Landmesser,M. John Chapman,Michel Farnier,Baris Gencer,Stephan Gielen,G. Kees Hovingh,Thomas F. Lüscher,David Sinning,Lale Tokgozoglu,Olov Wiklund,José Luis Zamorano,Fausto J. Pinto,Alberico L. Catapano +12 more
TL;DR: The causality of plasma low-density lipoprotein-cholesterol (LDL-C) and reduced LDL receptor-mediated LDL uptake in the pathophysiology of ASCVD has been established beyond any reasonable doubt and the need for additional LDL-C reduction with new therapeutic approaches which target these atherogenic particles is emphasized.
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Global strain rate imaging for the estimation of diastolic function in HFNEF compared with pressure-volume loop analysis
Mario Kasner,Regina Gaub,David Sinning,Dirk Westermann,Paul Steendijk,Wolfgang Hoffmann,Heinz-Peter Schultheiss,Carsten Tschöpe +7 more
TL;DR: Strain rate imaging is accurate in detecting increased LV stiffness in HFNEF, but it is not superior to already established TDI analysis including E/E' in patients with only mild degree of disease.
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Diastolic pressure–volume quotient (DPVQ) as a novel echocardiographic index for estimation of LV stiffness in HFpEF
TL;DR: 3D echocardiography allows accurate non-invasive measurements of diastolic pressure–volume quotient which correlates with invasive determined LV stiffness in HFpEF.
Journal ArticleDOI
The utility of speckle tracking imaging in the diagnostic of acute myocarditis, as proven by endomyocardial biopsy.
Mario Kasner,David Sinning,Felicitas Escher,Dirk Lassner,Uwe Kühl,Heinz-Peter Schultheiss,Carsten Tschöpe +6 more
TL;DR: proven by endomyocardial biopsy Mario Kasner, David Sinning, Felicitas Escher, Dirk Lassner, Uwe Kühl, Heinz-Peter Schultheiss, Carsten Tschöpe.
Journal ArticleDOI
Increased left ventricular stiffness impairs exercise capacity in patients with heart failure symptoms despite normal left ventricular ejection fraction.
David Sinning,Mario Kasner,Dirk Westermann,Karsten Schulze,Heinz-Peter Schultheiss,Carsten Tschöpe +5 more
TL;DR: Investigation of the influence of LV stiffness, determined by pressure-volume loop analysis obtained by conductance catheterization, on exercise capacity in HFNEF found CPET parameters such as peak oxygen uptake, peakoxy uptake at ventilatory threshold, and ventilation equivalent for carbon dioxide production at ventILatory threshold correlate with LV stiffness.