Davide Mauri

TL;DR: Neoadjuvant therapy was apparently equivalent to adjuvant therapy in terms of survival and overall disease progression and was associated with a statistically significant increased risk of loco-regional recurrence when radiotherapy without surgery was adopted.

TL;DR: The use of neoadjuvant systemic therapy for the treatment of primary breast cancer has constantly increased, especially in trials of new therapeutic regimens and therapies that use NST are aimed to precede and anticipate the results from larger adjuvant trials.

TL;DR: Inhibition of the aromatase system, in particular with third-generation aromatases inhibitors and inactivators, appears to be associated with statistically significant improved survival of patients with advanced breast cancer compared with standard hormonal treatments.

TL;DR: Treatment of periodontal disease with scaling and root planing during pregnancy cannot be considered to be an efficient way of reducing the incidence of preterm birth, and clear evidence that no such effect exists is provided.

TL;DR: Stepwise improvements in efficacy of chemotherapy and targeted treatments cumulatively have achieved major improvements in the survival of patients with advanced breast cancer.