Dean E. Hammermeister

TL;DR: An empirically derived database for diverse chemical structures of acute toxicity and corresponding modes of toxic action was developed through joint toxic action studies, the establishment of toxicodynamic profiles, and behavioral and dose‐response interpretation of 96‐h LC50 tests.

TL;DR: Results of this study did not reveal any robust correlations between brain and ovary aromatase activity and/or isoform-specific mRNA expression, but they were consistent with the current body of evidence related to teleost arom atase regulation, suggesting that increased understanding of the biology of aromatases may facilitate system-wide understanding of effects on aromat enzyme based on relatively few measured endpoints.

TL;DR: Electrophysiological responses of Mauthner cell-initiated startle responses provided a measure of neurological injury that is also directly correlated to a definitive and ecologically relevant behavioral endpoint.

TL;DR: Di-2-ethylhexyl-phthalate was not acutely toxic to any tested species at the highest tested concentrations and a daphnid mixture test with these three phthalates showed complete additivity, which suggests a similar mode of toxic action.

TL;DR: Growth of medaka was significantly reduced in the lowest exposure concentration during 28-day larval tests with aniline, 4-chloroaniline and 2,4-diaminotoluene, and the estimated maximum acceptable toxicant concentration was reported as less than the highest exposure concentration.