M
Michael D. Kahl
Researcher at United States Environmental Protection Agency
Publications - 82
Citations - 5595
Michael D. Kahl is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: Vitellogenin & Pimephales promelas. The author has an hindex of 40, co-authored 76 publications receiving 5273 citations. Previous affiliations of Michael D. Kahl include Pacific Northwest National Laboratory & University of Wisconsin–Superior.
Papers
More filters
Journal ArticleDOI
Description and evaluation of a short‐term reproduction test with the fathead minnow (Pimephales promelas)
TL;DR: The utility of this short‐term reproduction test with the fathead minnow is demonstrated for identifying chemicals that exert reproductive toxicity through alterations in endocrine systems controlled by estrogens and androgens.
Journal ArticleDOI
Effects of the androgenic growth promoter 17‐β‐trenbolone on fecundity and reproductive endocrinology of the fathead minnow
Gerald T. Ankley,Kathleen M. Jensen,Elizabeth A. Makynen,Michael D. Kahl,Joseph J. Korte,Michael W. Hornung,Tala R. Henry,Jeffrey S. Denny,Richard L. Leino,Vickie S. Wilson,Mary C. Cardon,Phillip C. Hartig,L. Earl Gray +12 more
TL;DR: The studies indicate that 17‐β‐trenbolone is a potent androgen and reproductive toxicant in fish and further studies are warranted to assess potential ecological risk.
Journal ArticleDOI
Evaluation of the aromatase inhibitor fadrozole in a short-term reproduction assay with the fathead minnow (Pimephales promelas).
Gerald T. Ankley,Michael D. Kahl,Kathleen M. Jensen,Michael W. Hornung,Joseph J. Korte,Elizabeth A. Makynen,Richard L. Leino +6 more
TL;DR: Results of this study indicate that the proposed fathead minnow assay should effectively identify test chemicals as potential aromatase inhibitors, both in the context of their reproductive toxicity and the specific mechanism of action.
Journal ArticleDOI
Aspects of basic reproductive biology and endocrinology in the fathead minnow (Pimephales promelas).
TL;DR: The fathead minnow (Pimephales promelas) has been proposed as a model species for assessing the adverse effects of endocrine-disrupting chemicals (EDCs) on reproduction and development as discussed by the authors.
Journal ArticleDOI
Linkage of biochemical responses to population‐level effects: A case study with vitellogenin in the fathead minnow (Pimephales promelas)
David H. Miller,Kathleen M. Jensen,Daniel L. Villeneuve,Michael D. Kahl,Elizabeth A. Makynen,Elizabeth J. Durhan,Gerald T. Ankley +6 more
TL;DR: Overall, the current study provides an example of how changes in a biomarker (VTG concentration) can be quantitatively translated into adverse effects at the individual and population levels.