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Deborah C. Rice
Researcher at United States Environmental Protection Agency
Publications - 10
Citations - 3746
Deborah C. Rice is an academic researcher from United States Environmental Protection Agency. The author has contributed to research in topics: Delayed puberty & Reference dose. The author has an hindex of 8, co-authored 10 publications receiving 3436 citations.
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Journal ArticleDOI
Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models.
Deborah C. Rice,Stan Barone +1 more
TL;DR: Of critical concern is the possibility that developmental exposure to neurotoxicants may result in an acceleration of age-related decline in function, and the fact that developmental neurotoxicity that results in small effects can have a profound societal impact when amortized across the entire population and across the life span of humans.
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Blood Lead Concentration and Delayed Puberty in Girls
Sherry G. Selevan,Deborah C. Rice,Karen A. Hogan,Susan Y. Euling,Andrea Pfahles-Hutchens,James Bethel +5 more
TL;DR: It is suggested that environmental exposure to lead may delay growth and pubertal development in girls, although confirmation is warranted in prospective studies.
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Environmental factors associated with a spectrum of neurodevelopmental deficits
TL;DR: This review focuses on two environmental agents, lead and methylmercury, to illustrate the neurobehavioral and cognitive effects that can result from early life exposures.
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Methods and rationale for derivation of a reference dose for methylmercury by the U.S. EPA.
TL;DR: This derivation used a series of benchmark dose analyses provided by a National Research Council panel convened to assess the health effects of methylmercury to identify several areas for which further information or analyses is needed, including the ratio of cord:maternal blood mercury concentration.
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The US EPA reference dose for methylmercury: sources of uncertainty.
TL;DR: It may be argued that derivation of a RfD for methylmercury is inappropriate, given that there does not appear to be a threshold for adverse neuropsychological effects based on available data.