D
Deepak Bhat
Researcher at Indian Institute of Technology Madras
Publications - 8
Citations - 79
Deepak Bhat is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Dynein & Chemical vapor deposition. The author has an hindex of 4, co-authored 8 publications receiving 56 citations. Previous affiliations of Deepak Bhat include Indian Institutes of Technology & Tata Institute of Fundamental Research.
Papers
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Journal ArticleDOI
Effectiveness of a dynein team in tug-of-war helped by reduced load-sensitivity of detachment: evidence from study of bidirectional endosome transport in Dictyostelium discoideum
Deepak Bhat,Manoj Gopalakrishnan +1 more
TL;DR: This analysis suggests that the load-dependent detachment of a dynein in a team is qualitatively different at sub-stall and super-stall loads, a conclusion which is likely to have implications in other situations involving collective effects of many motors.
Journal ArticleDOI
Transport of organelles by elastically coupled motor proteins.
Deepak Bhat,Manoj Gopalakrishnan +1 more
TL;DR: Interestingly, it is found in simulations that the stall force of a cargo elastically coupled to motors is independent of the stiffness of the linkers, and the load-sharing among the cargo-bound motors is observed.
Journal ArticleDOI
Effectiveness of a dynein team in a tug of war helped by reduced load sensitivity of detachment: evidence from the study of bidirectional endosome transport in D. discoideum
Deepak Bhat,Manoj Gopalakrishnan +1 more
TL;DR: In this paper, the authors analyzed the collective detachment time of dynein assembly in a team of oppositely pulling motors in a bidirectional motion of endosomes in the amoeba D. discoideum.
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Memory, bias, and correlations in bidirectional transport of molecular-motor-driven cargoes.
Deepak Bhat,Manoj Gopalakrishnan +1 more
TL;DR: It is shown, based on a study of the direction-reversal probabilities of the cargo using a purely stochastic (tug-of-war) model, that bidirectional motion of cellular cargoes is, in general, a correlated random walk.
Journal ArticleDOI
Stall force of a cargo driven by N interacting motor proteins
Deepak Bhat,Manoj Gopalakrishnan +1 more
TL;DR: In this paper, a generic one-dimensional model for an intracellular cargo driven by N motor proteins against an external applied force is presented, where the cargo motion is described by an over-damped Langevin equation, while motor dynamics is specified by hopping rates which follow a local detailed balance condition with respect to the change in energy per hopping event.