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Deepak Upadhaya

Researcher at Indian Veterinary Research Institute

Publications -  11
Citations -  143

Deepak Upadhaya is an academic researcher from Indian Veterinary Research Institute. The author has contributed to research in topics: Rhipicephalus microplus & Deltamethrin. The author has an hindex of 5, co-authored 10 publications receiving 73 citations.

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Acaricide resistance in Rhipicephalus microplus collected from selected districts of Madhya Pradesh, Uttar Pradesh and Punjab states of India.

TL;DR: The isolates of Rhipicephalus microplus collected from Madhya Pradesh, Punjab and Uttar Pradesh states of India were characterized using laboratory standardized adult immersion test (AIT) against macrocyclic lactone (ivermectin), synthetic pyrethroids, organophosphates (coumaphos and diazinon) and phenylpyrazole compounds (fipronil).
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Role of metabolic enzymes in conferring resistance to synthetic pyrethroids, organophosphates, and phenylpyrazole compounds in Rhipicephalus microplus

TL;DR: The enzymatic profiling revealed elevation in β-esterase, CYP450, and GST level in comparison to reference susceptible Indian veterinary research institute-I (IVRI-I) tick line, thus confirming the role of multiple mechanisms in conferring resistance in field isolates.
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Emergence of fipronil resistant Rhipicephalus microplus populations in Indian states

TL;DR: A significant variation of RF between both tests was found, which raises doubt about the suitability of larva-based assays in screening of fipronil resistance, and indicated possible cross-resistance between groups of acaricides in fipronsil-resistant tick populations.
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Standardization of tick specific biochemical tools for estimation of esterases, monooxygenases and glutathione S-transferase for characterization of acaricide resistance.

TL;DR: In all the nine heterogeneous field isolates, a significant correlation between resistance to synthetic pyrethroids and over-expression of esterases and monooxygenase was noticed and esterase and GST activities were significantly correlated with resistance to organophosphates.