D
Deepti Pandita
Researcher at Delhi Institute of Pharmaceutical Sciences and Research
Publications - 69
Citations - 2611
Deepti Pandita is an academic researcher from Delhi Institute of Pharmaceutical Sciences and Research. The author has contributed to research in topics: Docking (molecular) & Medicine. The author has an hindex of 21, co-authored 61 publications receiving 2034 citations. Previous affiliations of Deepti Pandita include University of Virginia Health System & University of North Dakota.
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Journal ArticleDOI
Dendrimers in drug delivery and targeting: Drug-dendrimer interactions and toxicity issues
TL;DR: The present review has focused on the different strategies of their synthesis, drug delivery and targeting, gene delivery and other biomedical applications, interactions involved in formation of drug-dendrimer complex along with characterization techniques employed for their evaluation, toxicity problems and associated approaches to alleviate their inherent toxicity.
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Solid lipid nanoparticles enhance oral bioavailability of resveratrol, a natural polyphenol
TL;DR: Stearic acid-based RLNs could act as promising sustained release system with enhanced bioavailability for resveratrol after oral administration and produce a significant 8.035 fold improvement in the oral bioavailability of resver atrol as compared to drug suspension.
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Functionalization of poly(amidoamine) dendrimers with hydrophobic chains for improved gene delivery in mesenchymal stem cells
José Luís Guedes dos Santos,Hugo Oliveira,Deepti Pandita,João Rodrigues,Ana Paula Pêgo,Pedro L. Granja,Helena Tomás +6 more
TL;DR: These new vectors show a remarkable capacity for mediating the internalization of pDNA with minimum cytotoxicity, being this effect positively correlated with the -CH(2)- content present in the hydrophobic corona.
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Updates on Aldose Reductase Inhibitors for Management of Diabetic Complications and Non-diabetic Diseases.
TL;DR: Adapting ARIs could prevent sepsis complications, prevent angiogenesis, ameliorate mild or asymptomatic diabetic cardiovascular autonomic neuropathy and appear to be a promising strategy for the treatment of endotoxemia and other ROS-induced inflammatory diseases.
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Non-Viral Gene Delivery to Mesenchymal Stem Cells: Methods, Strategies and Application in Bone Tissue Engineering and Regeneration
José Luís Guedes dos Santos,Deepti Pandita,João Rodrigues,Ana Paula Pêgo,Pedro L. Granja,Helena Tomás +5 more
TL;DR: An overview of the application of chemical and physical methods for non-viral gene delivery to MSCs is given and their use in tissue engineering and regenerative medicine therapeutic strategies highlighted using the example of bone tissue.