Journal•ISSN: 0168-3659
Journal of Controlled Release
Elsevier BV
About: Journal of Controlled Release is an academic journal published by Elsevier BV. The journal publishes majorly in the area(s): Drug delivery & Medicine. It has an ISSN identifier of 0168-3659. Over the lifetime, 12864 publications have been published receiving 895004 citations.
Topics: Drug delivery, Medicine, Drug carrier, Chemistry, Controlled release
Papers published on a yearly basis
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TL;DR: The basic characteristics of the EPR effect, particularly the factors involved, are described, as well as its modulation for improving delivery of macromolecular drugs to the tumor.
5,955 citations
TL;DR: In this paper, an exponential relation M t /M ∞ = kt n may be used to describe the Fickian and non-Fickian release behavior of release systems which are prepared by incorporation of a drug in a hydrophilic, initially glassy polymer.
3,522 citations
TL;DR: This review presents the most outstanding contributions in the field of biodegradable polymeric nanoparticles used as drug delivery systems from 1990 through mid-2000.
3,284 citations
TL;DR: In this paper, a simple exponential relation Mt/M∞ = ktn is introduced to describe the general solute release behavior of controlled release polymeric devices, where Mt is the fractional release, t is the release time, k is a constant, and n is the diffusional exponent characteristic of the release mechanism.
3,256 citations
TL;DR: This review summarizes historical and scientific perspectives of Doxil development and lessons learned from its development and 20 years of its use and demonstrates the obligatory need for applying an understanding of the cross talk between physicochemical, nano-technological, and biological principles.
3,189 citations