D
Denis Awany
Researcher at University of Cape Town
Publications - 10
Citations - 115
Denis Awany is an academic researcher from University of Cape Town. The author has contributed to research in topics: Microbiome & Population. The author has an hindex of 3, co-authored 8 publications receiving 67 citations.
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Journal ArticleDOI
Host and Microbiome Genome-Wide Association Studies: Current State and Challenges.
Denis Awany,Imane Allali,Shareefa Dalvie,Sian M. J. Hemmings,Kilaza Samson Mwaikono,Nicholas Ekow Thomford,Andres Gomez,Nicola Mulder,Emile R. Chimusa +8 more
TL;DR: The marked disparity in the sampling population of mGWAS carried out to date is highlighted and the critical need for inclusion of diverse populations is drawn attention.
Journal ArticleDOI
A broad survey of DNA sequence data simulation tools.
Shatha Alosaimi,Armand Bandiang,Noëlle van Biljon,Denis Awany,Prisca K Thami,Prisca K Thami,Milaine S S Tchamga,Anmol M. Kiran,Anmol M. Kiran,Olfa Messaoud,Radia Hassan,Jacquiline W Mugo,Azza Ahmed,Christian Domilongo Bope,Imane Allali,Gaston K. Mazandu,Gaston K. Mazandu,Nicola Mulder,Emile R. Chimusa +18 more
TL;DR: A review of DNA sequence simulation tools developed to date and evaluated 20 state-of-art DNA sequence Simulation tools on their ability to produce accurate reads based on their implemented sequence error model to suggest which tool is most appropriate for the given different scenarios.
Journal ArticleDOI
Dating admixture events is unsolved problem in multi-way admixed populations.
Emile R. Chimusa,Joel Defo,Prisca K Thami,Prisca K Thami,Prisca K Thami,Denis Awany,Delesa D. Mulisa,Imane Allali,Hassan Ghazal,Ahmed Moussa,Gaston K. Mazandu,Gaston K. Mazandu +11 more
TL;DR: Current dating admixture models are not sufficiently equipped to estimate ancient admixtures events and to identify multi-faceted admixture events in complex multi-way admixed populations.
Posted ContentDOI
Heritability jointly Explained by Host Genotype and Microbiome:Will Improve Traits Prediction?
Denis Awany,Emile R. Chimusa +1 more
TL;DR: The concept of heritability in GWAS and microbiome-wide association studies (MWAS), focusing on its estimation, from a statistical genetics perspective, is summarized and a possible method to incorporate the microbiome in the estimation ofHeritability in host GWAS is discussed.
Journal ArticleDOI
Clinical predictors of pulmonary tuberculosis among South African adults with HIV
Simon C Mendelsohn,Andrew Fiore-Gartland,Denis Awany,Humphrey Mulenga,Stanley Kimbung Mbandi,Michele Tameris,Gerhard Walzl,Kogieleum Naidoo,Gavin J. Churchyard,Thomas J. Scriba,Mark Hatherill +10 more
TL;DR: In this article , the authors explored the utility of clinical factors in predicting TB among people with HIV not seeking care, using multivariable LASSO regression with post-selection inference was used to test associations with Mtb sensitisation and TB disease.