Showing papers by "Denis Burkitt published in 1970"
TL;DR: The distribution of Burkitt's lymphoma is related to endemicity of malaria, not only on a world‐wide basis, but also in more detailed studies in East Africa, particularly in Uganda, and a causal relationship is suggested.
Abstract: The distribution of Burkitt's lymphoma is related to endemicity of malaria, not only on a world-wide basis, but also in more detailed studies in East Africa, particularly in Uganda. This geographical association, together with the diminished incidence of AS haemoglobulin in patients with this tumour and the increased susceptibility to lymphoma formation in mice infected with chronic malaria, suggest a causal relationship.
LYMPHOME DE BURKITT ET PALUDISME
Il existe un rapport entre la distribution du lymphome de Burkitt et l'endemicite du paludisme; ce fait a ete constate non seulement a l'echelle mondiale, mais aussi a la suite d'etudes plus detaillees menees notamment en Afrique orientale et en Ouganda. Cette association geographique, ainsi que la faible incidence de l'hemoglobine AS chez les sujets porteurs de cette tumeur et la sensibilite accrue a la formation de lymphomes chez les souris infectees par le paludisme chronique, donnent a penser qu'il y a la une relation de cause a effet.
112 citations
TL;DR: There is reason to suspect a common or related cause for diseases which are both associated with one another in their geographical distribution and tend to occur together in the same patients.
90 citations
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01 Jan 1970
TL;DR: This tumor was first identified as a clinical syndrome early in 1957 by the observation that the age distribution among patients with the different tumors was similar and the geographical distribution identical, and the histological and cytological features were shown to be identical.
54 citations
Book•
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TL;DR: In the early 1970s, workers in different parts of tropical Africa had recognized an undue prevalence of a number of apparently unconnected tumors in children, including retinoblastoma, neuroblastoma, sarcomas of the upper and lower jaws and granulosa-cell tumors of the ovary as discussed by the authors.
Abstract: Before the indentification of the tumor syndrome which subsequently became known as Burkitt’s lymphoma, workers in different parts of tropical Africa had recognized an undue prevalence of a number of apparently unconnected tumors in children. These included retinoblastoma, neuroblastoma, sarcomas of the upper and lower jaws and granulosa-cell tumors of the ovary, all of which were composed of small round cells with similar histological appearances. A flaccid paraplegia of rapid onset without evidence of vertebral collapse and tumors of the long bones of the limbs were seen more frequently than might be expected.
11 citations
2 citations