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Dennis D. Kunkel

Researcher at University of Washington

Publications -  37
Citations -  3643

Dennis D. Kunkel is an academic researcher from University of Washington. The author has contributed to research in topics: Hippocampal formation & Granule cell. The author has an hindex of 28, co-authored 37 publications receiving 3558 citations. Previous affiliations of Dennis D. Kunkel include Washington University in St. Louis.

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Heteromultimeric K+ channels in terminal and juxtaparanodal regions of neurons

TL;DR: The co-localization of two Shaker-like voltage-gated K+-channel proteins is described, indicating that the two polypeptides occur in subcellular regions where rapid membrane repolarization may be important and that they form heteromultimeric channels in vivo.
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Local circuit interactions between oriens/alveus interneurons and CA1 pyramidal cells in hippocampal slices: electrophysiology and morphology.

TL;DR: Electrophysiological and anatomical results suggest that O/A interneurons make synaptic contact with pyramidal cells and may mediate feedforward and feedback inhibition onto CA 1 pyramid cells.
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Physiologic and Morphologic Characteristics of Granule Cell Circuitry in Human Epileptic Hippocampus

TL;DR: The data suggest that granule cell bursting activity is at least in part a function of compromised synaptic inhibition, since levels of γ‐aminobutyric acid (GABA) blockade that are generally subthreshold for burst induction were epileptogenic in some tissue samples from human epileptic hippocampus.
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Axon arbors and synaptic connections of hippocampal mossy cells in the rat in vivo

TL;DR: The axon collateralization patterns and synaptic connections of intracellularly labeled and electrophysiologically identified mossy cells were studied in rat hippocampus and indicated that more than 90% of mossy cell synaptic contacts in the ipsilateral hippocampus are onto spines of proximal dendrites of presumed granule cells.
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Synaptic connections of dentate granule cells and hilar neurons: results of paired intracellular recordings and intracellular horseradish peroxidase injections.

TL;DR: These studies provide the first step towards determining the functional interactions of the various cell types in the fascia dentata, with granule cells having strong excitatory effects on mossy cells and interneurons.