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Devadasan Velmurugan

Researcher at University of Madras

Publications -  550
Citations -  3409

Devadasan Velmurugan is an academic researcher from University of Madras. The author has contributed to research in topics: Ring (chemistry) & Dihedral angle. The author has an hindex of 24, co-authored 544 publications receiving 2893 citations. Previous affiliations of Devadasan Velmurugan include SRM University & Bharathiar University.

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Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19.

Nisha Muralidharan, +3 more
- 03 May 2021 - 
TL;DR: The combination of three known drugs, lopinavir, oseltamivir and ritonavir has been proposed to control the virulence to a great extent in COVID-19 affected patients within 48 hours and showed a better binding energy than that of individual drugs.
Journal Article

Biosynthesis of gold nanoparticles by actinomycete Streptomyces viridogens strain HM10.

Ramasamy Balagurunathan, +3 more
- 01 Oct 2011 - 
TL;DR: Actinomycete strain HM10 reported in this study is a newly added source for the biosynthesis of gold nanoparticles, which showed good antibacterial activity against S. aureus and E. coli in well-diffusion method.
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Identification of Natural Compound Inhibitors for Multidrug Efflux Pumps of Escherichia coli and Pseudomonas aeruginosa Using In Silico High-Throughput Virtual Screening and In Vitro Validation

Vasudevan Aparna, +4 more
- 15 Jul 2014 - 
TL;DR: Good correlation between in silico screening and positive efflux inhibitory activity in vitro means that lanatoside C and diadzein could be promising efflux pump inhibitors and effective to use in combination therapy against drug resistant strains of P. aeruginosa and E. coli.
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Identification of a Novel Family of Snake Venom Proteins Veficolins from Cerberus rynchops Using a Venom Gland Transcriptomics and Proteomics Approach

OmPraba G, +8 more
- 05 Apr 2010 - 
TL;DR: The combined approach of transcriptomics and proteomics revealed that C. rynchops venom is among the least complex snake venom characterized to date despite the presence of a new family of snake venom proteins.
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Screening dietary flavonoids for the reversal of P-glycoprotein-mediated multidrug resistance in cancer.

S. Mohana, +9 more
- 19 Jul 2016 - 
TL;DR: Quercetin and rutin were the highly desirable flavonoids for the inhibition of P-gp transport function and they significantly reduced resistance in cytotoxicity assays to paclitaxel in P- gp overexpressing MDR cell lines, and may be considered as potential chemosensitizing agents to overcome multidrug resistance in cancer.