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Devaleena S. Pradhan

Researcher at Georgia State University

Publications -  25
Citations -  726

Devaleena S. Pradhan is an academic researcher from Georgia State University. The author has contributed to research in topics: Zebra finch & Dehydroepiandrosterone. The author has an hindex of 12, co-authored 22 publications receiving 626 citations. Previous affiliations of Devaleena S. Pradhan include University of California & University of British Columbia.

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Neurosteroids, immunosteroids, and the Balkanization of endocrinology.

TL;DR: It is proposed that the shift to local synthesis and regulation of steroids within target tissues represents a "Balkanization" of the endocrine system, whereby individual tissues and organs may become capable of autonomously synthesizing and modulating local steroid signals, perhaps independently of the HPG and HPA axes.
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Aggressive interactions rapidly increase androgen synthesis in the brain during the non-breeding season

TL;DR: The data suggest that territorial challenges rapidly increase endogenous NAD(+) levels or increase 3beta-HSD activity specifically within a NAD-rich subcellular compartment and suggest a shift from systemic to local sex steroid signaling in the non-breeding season.
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Dehydroepiandrosterone and corticosterone are regulated by season and acute stress in a wild songbird: jugular versus brachial plasma.

TL;DR: The data suggest that acute stress specifically affects the balance between DHEA synthesis and metabolism in the brain during molt, when systemic levels of CORT and D HEA are low.
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Rapid estrogen regulation of DHEA metabolism in the male and female songbird brain.

TL;DR: The first data to show a rapid effect of estrogens on the songbird brain are shown and suggest that rapid estrogen effects differ between male and female brains.
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3β-HSD activates DHEA in the songbird brain

TL;DR: Evidence that DHEA treatment can stimulate song behavior and the growth of neural circuits controlling song behavior is described, and brain 3β-HSD and aromatase can work in concert to locally metabolize D HEA into active androgens and estrogens, which are critical for controlling behavior and robust adult neuroplasticity in songbirds.