D
Devin V. McAllister
Researcher at Georgia Institute of Technology
Publications - 13
Citations - 3035
Devin V. McAllister is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: Transdermal & Vaccination. The author has an hindex of 9, co-authored 13 publications receiving 2698 citations. Previous affiliations of Devin V. McAllister include Micron Technology.
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Journal ArticleDOI
Microfabricated microneedles: a novel approach to transdermal drug delivery.
TL;DR: These microneedle arrays could be easily inserted into skin without breaking and were shown to increase permeability of human skin in vitro to a model drug, calcein, by up to 4 orders of magnitude.
Journal ArticleDOI
Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies
Devin V. McAllister,Ping M. Wang,Shawn P. Davis,Jung-Hwan Park,Paul J. Canatella,Mark G. Allen,Mark R. Prausnitz +6 more
TL;DR: Microfabrication techniques for silicon, metal, and biodegradable polymer microneedle arrays having solid and hollow bores with tapered and beveled tips and feature sizes from 1 to 1,000 μm allowed flow of microliter quantities into skin in vivo, including microinjection of insulin to reduce blood glucose levels in diabetic rats.
Journal ArticleDOI
Microfabricated microneedles for gene and drug delivery.
TL;DR: Microneedles have been developed to reduce needle insertion pain and tissue trauma and to provide controlled delivery across the skin, and these needles have been shown to be robust enough to penetrate skin and dramatically increase skin permeability to macromolecules.
Journal ArticleDOI
The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trial
Nadine Rouphael,Michele Paine,Regina Mosley,Sebastien Henry,Devin V. McAllister,Haripriya Kalluri,Winston P. Pewin,Paula M. Frew,Tianwei Yu,Natalie J. Thornburg,Sarah Kabbani,Lilin Lai,Elena V. Vassilieva,Ioanna Skountzou,Richard W. Compans,Mark J. Mulligan,Mark R. Prausnitz,Allison Beck,Srilatha Edupuganti,Sheila Heeke,Colleen F. Kelley,Wendy Nesheim +21 more
TL;DR: Safety, immunogenicity, and acceptability of the first-in-man study on single, dissolvable microneedle patch vaccination against influenza are described and secondary safety outcomes are new-onset chronic illnesses within 180 days and unsolicited adverse events within 28 days, all analysed by intention to treat.
Proceedings ArticleDOI
Micromachined needles for the transdermal delivery of drugs
TL;DR: These microneedles were fabricated using the Black Silicon Method, which is a reactive ion etching process in which an SF/sub 6//O/sub 2/ plasma etches silicon anisotropically and demonstrated excellent mechanical properties and skin permeability to calcein, a model drug, by up to four orders of magnitude.