D
Dharam P. Agarwal
Researcher at University of Hamburg
Publications - 76
Citations - 2891
Dharam P. Agarwal is an academic researcher from University of Hamburg. The author has contributed to research in topics: Aldehyde dehydrogenase & Alcohol dehydrogenase. The author has an hindex of 25, co-authored 76 publications receiving 2805 citations.
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Journal ArticleDOI
Distribution of ADH2 and ALDH2 genotypes in different populations
H. W. Goedde,Dharam P. Agarwal,G. Fritze,Doris Meier-Tackmann,Surjit Singh,G. Beckmann,Kuldeep Bhatia,L. Z. Chen,Bingliang Fang,R. Lisker,Y. K. Paik,Francisco Rothhammer,Nilmani Saha,B. Segal,L. M. Srivastava,A. Czeizel +15 more
TL;DR: The atypical ALDH2 gene (ALDH22) was found to be extremely rare in Caucasoids, Negroids, Papua New Guineans, Australian Aborigines and Aurocanians and this mutant gene was finding to be widely prevalent among the Mongoloids.
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Cardioprotective effects of light-moderate consumption of alcohol: a review of putative mechanisms.
TL;DR: Alcohol reduces the risk of coronary vascular diseases both by inhibiting the formation of atheroma and decreasing the rate of blood coagulation, according to the plausible mechanisms for the putative cardioprotective effects.
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Racial differences in alcohol sensitivity: A new hypothesis
TL;DR: The data suggest that the initial alcohol sensitivity in Japanese might be due to a delayed oxidation of acetaldehyde rather than its higher than normal production by atypical alcohol dehydrogenase.
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Racial differences in biological sensitivity to ethanol: the role of alcohol dehydrogenase and aldehyde dehydrogenase isozymes
TL;DR: The findings suggest that the alcohol sensitivity quite common in individuals of Mongoloid origin might be due to delayed oxidation of acetaldehyde by an unusual type of ALDH.
Journal ArticleDOI
Pharmacogenetics of alcohol metabolism and alcoholism.
Dharam P. Agarwal,H. W. Goedde +1 more
TL;DR: Taken together, Orientals who possess an atypical ALDH2 gene are more sensitive to acute responses to alcohol, tend to be discouraged from drinking alcohol, and consequently are at lower risk of developing alcohol-related disorders.