Diana C. Castro-Rodríguez

TL;DR: This study provides evidence for programming‐ageing interactions and indicates that maternal obesity predisposes to metabolic dysfunction in male and female offspring and high‐fat diet consumption prior to and throughout pregnancy and lactation accelerates offspring metabolic ageing.

TL;DR: This review addresses the relationship between adverse perinatal insults and its negative impact on offspring development and presents some maternal intervention studies in animal models, such as maternal nutrition (diet modification, antioxidants, omega-3-6, probiotics) or physical activity, which can prevent or alleviate negative outcomes in both mother and offspring.

TL;DR: It is concluded that maternal low‐protein diet impairs spatial acquisition and memory retention in male offspring, and that alterations in hippocampal presynaptic (MF), postsynaptic (spines) elements and higher glucocorticoid levels are potential mechanisms to explain these learning and memory deficits.

TL;DR: Novel evidence is provided that dietary intervention with L. mesenteroides SD23 improves metabolic dysfunction related to obesity in HFD-fed mice, and the parameters evaluated in the CP were similar to the C.

TL;DR: This review addresses the relationship between adverse perinatal insults and its negative impact on offspring development and presents some maternal intervention studies such as diet modification, probiotic consumption, or maternal exercise to prevent or alleviate the negative outcomes in both the mother and her child.