D
Diana Giannarelli
Researcher at Sapienza University of Rome
Publications - 640
Citations - 19302
Diana Giannarelli is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 60, co-authored 544 publications receiving 15987 citations. Previous affiliations of Diana Giannarelli include Università Campus Bio-Medico & University of Turin.
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Journal ArticleDOI
Systematic Pelvic Lymphadenectomy vs No Lymphadenectomy in Early-Stage Endometrial Carcinoma: Randomized Clinical Trial
Pierluigi Benedetti Panici,Stefano Basile,Francesco Maneschi,Andrea Lissoni,Mauro Signorelli,Giovanni Scambia,Roberto Angioli,Saverio Tateo,Giorgia Mangili,Dionyssios Katsaros,Gaetano Garozzo,Elio Campagnutta,Nicoletta Donadello,Stefano Greggi,Mauro Melpignano,Francesco Raspagliesi,Nicola Ragni,Gennaro Cormio,Roberto Grassi,Massimo Franchi,Diana Giannarelli,Roldano Fossati,Valter Torri,M. Amoroso,Clara Crocè,Costantino Mangioni +25 more
TL;DR: Although systematic pelvic lymphadenectomy statistically significantly improved surgical staging, it did not improve disease-free or overall survival.
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Prevention of VTE in orthopedic surgery patients
Federico Spandonaro,Rossella Letizia Mancusi,Lorenzo Terranova,Diana Giannarelli,Paolo Grossi,Davide Imberti,Emilio Mazza +6 more
TL;DR: A model of budget impact, in the perspective of the Italian NHS, is built from the data related to cases of major surgical orthopedic procedures and a meta-analysis on the pivotal RCT, which aims to measure the differential effects in terms of prevention of VTE, showing that the financial impact of the NOA in the prophylaxis of major Orthopedic surgery is not particularly relevant.
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Systematic Aortic and Pelvic Lymphadenectomy Versus Resection of Bulky Nodes Only in Optimally Debulked Advanced Ovarian Cancer: A Randomized Clinical Trial
Pierluigi Benedetti Panici,Angelo Maggioni,Neville F. Hacker,Fabio Landoni,Sven Ackermann,Elio Campagnutta,Karl Tamussino,Raimund Winter,Antonio Pellegrino,Stefano Greggi,Roberto Angioli,Natalina Manci,Giovanni Scambia,Tiziana Dell'Anna,Roldano Fossati,Irene Floriani,Rita Rossi,Roberto Grassi,Giuseppe Favalli,Francesco Raspagliesi,Diana Giannarelli,Luca Martella,Costantino Mangioni +22 more
TL;DR: Systematic lymphadenectomy improves progression-free but not overall survival in women with optimally debulked advanced ovarian carcinoma, and the percentage of patients requiring blood transfusions was higher in the systematic lymphenectomy arm than in the no-lymphadenectomy arm.
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Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary Cancers.
Luisa Carbognin,Sara Pilotto,Michele Milella,Vanja Vaccaro,Matteo Brunelli,Anna Caliò,Federica Cuppone,Isabella Sperduti,Diana Giannarelli,Marco Chilosi,Vincenzo Bronte,Aldo Scarpa,Emilio Bria,Giampaolo Tortora +13 more
TL;DR: Overall, the three antibodies provide a significant differential effect in terms of activity according to PD-L1 expression on tumor cells, which seems to be more robust for anti-PD-1 antibody (nivolumab and pembrolizumab), and in the context of advanced melanoma and NSCLC.
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Neoadjuvant Chemotherapy and Radical Surgery Versus Exclusive Radiotherapy in Locally Advanced Squamous Cell Cervical Cancer: Results From the Italian Multicenter Randomized Study
Pierluigi Benedetti-Panici,Stefano Greggi,Alessandro Colombo,M. Amoroso,Daniela Smaniotto,Diana Giannarelli,Gianni Amunni,Francesco Raspagliesi,Paolo Zola,Costantino Mangioni,Fabio Landoni +10 more
TL;DR: Although significant only for the stage IB2 to IIB group, a survival benefit seems to be associated with the NACT+RS compared with conventional RT, which had a significant impact on OS and PFS.