D
Diana Metodiewa
Researcher at University of Alberta
Publications - 12
Citations - 312
Diana Metodiewa is an academic researcher from University of Alberta. The author has contributed to research in topics: Lactoperoxidase & Superoxide dismutase. The author has an hindex of 7, co-authored 12 publications receiving 310 citations.
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Journal ArticleDOI
Generation of Superoxide and Tyrosine Peroxide as a Result of Tyrosyl Radical Scavenging by Glutathione
TL;DR: Using horseradish peroxidase to generate tyrosyl radicals and investigating the fate of the superoxide radicals shows that both pathways are undesirable for the cell and are effectively suppressed only if GSH as a radical scavenger acts in concert with SOD.
Journal ArticleDOI
Evidence for a peroxidatic oxidation of norepinephrine, a catecholamine, by lactoperoxidase.
TL;DR: The results of a rapid scan and spectrophotometric investigation of the reaction clearly indicate a normal peroxidatic pathway of catecholamine degradation.
Journal ArticleDOI
The reactions of horseradish peroxidase, lactoperoxidase, and myeloperoxidase with enzymatically generated superoxide.
Diana Metodiewa,H. B. Dunford +1 more
TL;DR: It is tentatively concluded that in all cases compound III is formed in a two-step reaction of native enzyme with superoxide.
Journal ArticleDOI
Horseradish peroxidase-catalyzed aerobic oxidation and peroxidation of indole-3-acetic acid: I. Optical spectra
TL;DR: In this article, a study of the indole-3-acetate reaction with horse-radish peroxidase, in the absence or presence of hydrogen peroxide, has been performed, employing rapid scan and conventional spectrophotometry.
Journal ArticleDOI
Oxidation of the substituted catechols dihydroxyphenylalanine methyl ester and trihydroxyphenylalanine by lactoperoxidase and its compounds
TL;DR: The reactions of native lactoperoxidase and its compound II with two substituted catechols have been investigated by ESR spin stabilization and spin trapping and by rapid scan and conventional spectrophotometric techniques.