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Diana Samson

Researcher at Imperial College London

Publications -  15
Citations -  736

Diana Samson is an academic researcher from Imperial College London. The author has contributed to research in topics: Multiple myeloma & Transplantation. The author has an hindex of 10, co-authored 15 publications receiving 715 citations.

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Guidelines on the diagnosis and management of multiple myeloma 2005

TL;DR: These revised and updated guidelines include new sections on imaging and the management of skeletal disease, cover new developments in disease classification and staging and the use of new therapeutic approaches, such as thalidomide, bortezomib and reduced-intensity allogeneic transplantation.
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Predictive factors for survival in myeloma patients who undergo autologous stem cell transplantation: a single-centre experience in 211 patients

TL;DR: It is concluded that ASCT is safe and effective and the outcome is independent of age, time from diagnosis, previous treatment and conditioning regimen and the international prognostic index at transplant.
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Plasmacytoma relapses in the absence of systemic progression post-high-dose therapy for multiple myeloma.

TL;DR: 15 out of 163 patients who underwent SCT and relapsed with plasmacytomas only without evidence of bone marrow disease progression are presented here, with cases of unconventional disease recurrence likely to be seen due to sub‐clinical seeding of tumour cells suggestive of the presence of an extramedullary (EM) clone of plasma cells with a high degree of chemoresistance.
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Autologous stem cell transplantation in multiple myeloma: improved survival in nonsecretory multiple myeloma but lack of influence of age, status at transplant, previous treatment and conditioning regimen. A single-centre experience in 127 patients.

TL;DR: It is concluded that ASCT is a safe and effective procedure even in resistant cases, independent of age, time from diagnosis, previous treatment and conditioning regimen, but there was a tendency for better survival in the nonsecretory patients.
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CD34+-selected peripheral blood progenitor cell transplantation in patients with multiple myeloma: tumour cell contamination and outcome

TL;DR: There was no difference in event‐free survival (EFS) between the CD34+‐selected group and the unselected group (median 21 and 26 months, respectively, P=ns).