D
Didier Lebrec
Researcher at French Institute of Health and Medical Research
Publications - 405
Citations - 20935
Didier Lebrec is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Portal hypertension & Portal venous pressure. The author has an hindex of 76, co-authored 404 publications receiving 20109 citations. Previous affiliations of Didier Lebrec include Paris Diderot University.
Papers
More filters
Journal ArticleDOI
Propranolol for prevention of recurrent gastrointestinal bleeding in patients with cirrhosis: a controlled study
TL;DR: It is concluded that continuous administration of propranolol by mouth is effective in preventing recurrent gastrointestinal bleeding in patients with cirrhosis.
Journal ArticleDOI
Portal hypertension, size of esophageal varices, and risk of gastrointestinal bleeding in alcoholic cirrhosis
TL;DR: In patients with alcoholic cirrhosis, the degree of portal hypertension has no predictive value for the risk of gastrointestinal bleeding and large-sized esophageal varices are associated with a high risk of occurrence or recurrence of gastrointestinal bleed and could be taken into account for a better selection of patients for portacaval shunt.
Journal ArticleDOI
Pulmonary hypertension complicating portal hypertension: prevalence and relation to splanchnic hemodynamics.
TL;DR: The prevalence of pulmonary hypertension in 507 patients hospitalized with portal hypertension but without known pulmonary hypertension who underwent cardiac catheterization was prospectively studied and no significant relation was found between elevated pulmonary vascular resistance and increased portal pressure, zzygos blood flow, or cardiac index.
Journal ArticleDOI
Beta-adrenergic-antagonist drugs in the prevention of gastrointestinal bleeding in patients with cirrhosis and esophageal varices. An analysis of data and prognostic factors in 589 patients from four randomized clinical trials. Franco-Italian Multicenter Study Group.
Thierry Poynard,Paul Calès,Linda Pasta,G. Idéo,Jean-Pierre Pascal,Luigi Pagliaro,Didier Lebrec +6 more
TL;DR: In this paper, the authors analyzed data on individual patients from four randomized, controlled trials to assess the efficacy of the beta-adrenergic-antagonist drug therapy for the prevention of initial episodes of gastrointestinal bleeding.
Journal ArticleDOI
Terlipressin in patients with cirrhosis and type 1 hepatorenal syndrome: a retrospective multicenter study.
Richard Moreau,François Durand,Thierry Poynard,Christian Duhamel,Cervoni Jp,Philippe Ichai,Armand Abergel,Chantal Halimi,Mathieu Pauwels,Jean-Pierre Bronowicki,E. Giostra,Cathy Fleurot,Danielle Gurnot,Olivier Nouel,Philippe Renard,Michel Rivoal,Pierre Blanc,Dimitri Coumaros,Sylvie Ducloux,Stephane Levy,Alexandre Pariente,Perarnau Jm,Jean Roche,Myriam Scribe–Outtas,Dominique Valla,B Bernard,Didier Samuel,Joël Butel,Antoine Hadengue,Andrzej Platek,Didier Lebrec,Jean François Cadranel +31 more
TL;DR: In patients with type 1 HRS, terlipressin-induced improved renal function is associated with an increase in survival, and a randomized trial investigating the effect of ter Lipressin on survival in patients with types 1 and 2 HRS should be performed.