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Dietmar Volz
Researcher at Hoffmann-La Roche
Publications - 11
Citations - 268
Dietmar Volz is an academic researcher from Hoffmann-La Roche. The author has contributed to research in topics: Gantenerumab & Biomarker (medicine). The author has an hindex of 5, co-authored 11 publications receiving 237 citations.
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Journal ArticleDOI
Effect of aleglitazar on cardiovascular outcomes after acute coronary syndrome in patients with type 2 diabetes mellitus: the AleCardio randomized clinical trial.
A. Michael Lincoff,Jean-Claude Tardif,Gregory G. Schwartz,Stephen J. Nicholls,Lars Rydén,Bruce Neal,Klas Malmberg,Klas Malmberg,Hans Wedel,John B. Buse,Robert R. Henry,Arlette Weichert,Ruth Cannata,Anders Svensson,Dietmar Volz,Diederick E. Grobbee +15 more
TL;DR: Findings do not support the use of aleglitazar in this setting with a goal of reducing cardiovascular risk and the trial was terminated on July 2, 2013 due to futility for efficacy at an unplanned interim analysis and increased rates of safety end points.
Journal ArticleDOI
Effects of the dual peroxisome proliferator-activated receptor activator aleglitazar in patients with Type 2 Diabetes mellitus or prediabetes.
Erland Erdmann,Robert M. Califf,Hertzel C. Gerstein,Klas Malmberg,Klas Malmberg,Luis M. Ruilope,Gregory G. Schwartz,Hans Wedel,Dietmar Volz,Marc Ditmarsch,Anders Svensson,Monica Bengus +11 more
TL;DR: Even within a short duration of exposure, aleglitazar was associated with excess adverse events, corroborating the findings of a larger and longer trial in T2D and holding little promise for CV therapeutics.
Journal ArticleDOI
Efficacy and safety of gantenerumab in prodromal Alzheimer’s disease: Results from scarlet road—a global, multicenter trial
Robert Lasser,Susanne Ostrowitzki,Philip Scheltens,Mercè Boada,Bruno Dubois,Ernest Dorflinger,Bogdan Balas,Tania Nikolcheva,Dietmar Volz,Elizabeth Ashford,Chris J. Edgar,George Garibaldi,Paulo Fontoura,Luca Santarelli +13 more
TL;DR: The aim of this book is to contribute towards the humanizing of memory and the promotion of a positive image of the past.
Journal ArticleDOI
Biomarker data from scarlet road: A global phase 3 study of gantenerumab in patients with prodromal Alzheimer's disease
Philip Scheltens,Tania Nikolcheva,Robert Lasser,Susanne Ostrowitzki,Mercè Boada,Bruno Dubois,Ernest Dorflinger,Dietmar Volz,Udo Eichenlaub,Christina Rabe,Tobias Bittner,Markus Schmitz,Chris J. Edgar,George Garibaldi,Paulo Fontoura,Luca Santarelli +15 more
TL;DR: The aim of this book is to provide a history of memory and aging in Toulouse and to contribute towards the humanizing of the city.