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Dietrich Samoray
Researcher at University of Basel
Publications - 2
Citations - 513
Dietrich Samoray is an academic researcher from University of Basel. The author has contributed to research in topics: Cyclic di-GMP & EAL domain. The author has an hindex of 2, co-authored 2 publications receiving 484 citations.
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Structural basis of activity and allosteric control of diguanylate cyclase
TL;DR: It is inferred that, in solution, the two DGC domains of a dimer align in a two-fold symmetric way to catalyze c-diGMP synthesis and sets an upper limit for the concentration of this second messenger in the cell.
Journal ArticleDOI
Inherent regulation of EAL domain-catalyzed hydrolysis of second messenger cyclic di-GMP.
Amit Sundriyal,Claudia Massa,Dietrich Samoray,Fabian Zehender,Timothy Sharpe,Urs Jenal,Tilman Schirmer +6 more
TL;DR: Biophysical and functional analyses are used to show that the isolated EAL domain of a PDE from Escherichia coli (YahA) is in a fast thermodynamic monomer-dimer equilibrium, and that the domain is active only in its dimeric state.