D
Dilek Cevik
Researcher at Bilkent University
Publications - 7
Citations - 288
Dilek Cevik is an academic researcher from Bilkent University. The author has contributed to research in topics: Gene & Cancer. The author has an hindex of 5, co-authored 6 publications receiving 199 citations. Previous affiliations of Dilek Cevik include Joseph Fourier University.
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Journal ArticleDOI
Genetics and epigenetics of liver cancer.
Cigdem Ozen,Gokhan Yildiz,Gokhan Yildiz,Alper Tunga Dagcan,Dilek Cevik,Dilek Cevik,Aysegul Ors,Aysegul Ors,Umur Keles,Hande Topel,Mehmet Ozturk,Mehmet Ozturk +11 more
TL;DR: Genetic and epigenetic studies on HCC may help to understand better its mechanisms and provide new tools for early diagnosis and therapy, and identify novel biomarkers and therapeutic targets for HCC.
Journal ArticleDOI
Potential Applications of NRF2 Modulators in Cancer Therapy
Emiliano Panieri,Aleksandra Buha,Pelin Telkoparan-Akillilar,Dilek Cevik,Demetrios Kouretas,Aristidis S. Veskoukis,Zoi Skaperda,Aristidis Tsatsakis,David R. Wallace,Sibel Suzen,Luciano Saso +10 more
TL;DR: The dual roles of the NRF2-KEAP1 pathway in cancer promotion and inhibition are focused on, describing the mechanisms of its activation and potential therapeutic strategies based on the use of context-specific modulation of NRf2.
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Common telomerase reverse transcriptase promoter mutations in hepatocellular carcinomas from different geographical locations
TL;DR: TERT promoter is one of most frequent mutational targets in liver cancer, and hepatocellular carcinogenesis is highly associated with the loss of telomere-dependent cellular senescence control.
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Therapeutic Targeting of the NRF2 Signaling Pathway in Cancer.
TL;DR: In this article, the authors discuss the mechanisms of normal and deregulated nuclear factor-erythroid 2-related factor 2 (NRF2) signaling pathway focusing on its cancer-related functions.
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Identification of miR-17, miR-21, miR-27a, miR-106b and miR-222 as endoplasmic reticulum stress-related potential biomarkers in circulation of patients with atherosclerosis.
TL;DR: In this article, the expression levels of microRNAs (miRNAs) and CHOP gene in the circulation of atherosclerosis patients compared to healthy controls were investigated to establish a link between ER-stress and atherosis.