Showing papers by "Dillip Kumar Chand published in 2023"
TL;DR: In this paper , a platinum-II-based macrocycle has been synthesized and characterized by NMR and ESI-MS, and single crystal X-ray diffraction study reveals that the macrocycle possesses a well-defined cavity.
TL;DR: In this paper , a self-assembled coordination cage in water has been shown to have an efficient chloride binding ability, which occurs selectively even in the presence of biologically abundant anionic systems.
Abstract: Invited for the cover of this issue is the group of Dillip Kumar Chand at the Indian Institute of Technology Madras. The image depicts the efficient chloride binding ability of a designer self-assembled coordination cage in water. The binding occurs selectively even in presence of models of biologically abundant anionic systems. Read the full text of the article at 10.1002/chem.202300891.
TL;DR: Chand et al. as discussed by the authors used a supramolecular halide catcher to catch chloride from an aqueous solution containing the biologically most abundant essential anions, achieving up to nanomolar affinity.
Abstract: A supramolecular halide catcher catches chloride exclusively from an aqueous solution containing the biologically most abundant essential anions. Multiple noncovalent interactions are involved in the deep enclosure of the designer self-assembled coordination cage for chloride binding. Impressively, chloride is captured with up to nanomolar affinity in aqueous solutions. More information can be found in the Research Article by D. K. Chand and co-workers (DOI: 10.1002/chem.202300891).
TL;DR: A template-free Pd2L4 cage exhibiting high selectivity for medium-sized halides (i.e., Cl-, Br-) in water owing to the size-discriminatory nature of the cage cavity was reported in this paper .
Abstract: Selective binding of chloride over other most abundant anions in living organisms is pivotal due to its essential role in physiological functions. Herein we report a template-free Pd2L4 cage exhibiting high selectivity for medium-sized halides (i.e., Cl-, Br-) in water owing to the size-discriminatory nature of the cage cavity. In pure water, this cage displays high selectivity, and micromolar affinity for chloride. The cage shows no binding towards other biologically more abundant essential anions such as phosphates, carboxylates, and bicarbonate. This cage shows an unprecedented nanomolar affinity with 1:1 binding stoichiometry for chloride in aqueous-DMSO media. This high affinity was achieved with the best use of traditional hydrogen bonding and electrostatic interactions as confirmed by single-crystal X-ray diffraction analysis. This well-defined cage sequestrates F- by cleaving B-F bond from BF4- in a facile manner in non-polar solvent media or in the presence of excess ligand. This cage also demonstrates sub-ppm level chloride capture that is present in commercial D2O samples.