Dilmurodjon Eshmuminov

TL;DR: A liver perfusion machine that integrates multiple core physiological functions, including automated management of glucose levels and oxygenation, waste-product removal and hematocrit control is developed in a stepwise fashion using pig livers.

TL;DR: Assessment of flavin, a marker of mitochondrial complex I injury, in the perfusate provides a fast prediction of liver graft function and loss during ex situ MP before implantation, which may have high clinical relevance, as liver grafts from extended DBD or DCD donors carry considerable risks for recipients.

TL;DR: The aim of this study was to compare available strategies using a two‐stage approach in extended hepatectomy.

TL;DR: A widely accepted definition of PT is lacking and a correlation with the risk of POPF is based on subjective evaluation, which is still acceptable, and classification of PT into 2-groups is more reasonable than classification into 3-groups.

TL;DR: The transplantation of a human liver discarded by all centers is reported, which could be preserved for several days using ex situ normothermic machine perfusion and exhibited normal function, with minimal reperfusion injury and the need for only a minimal immunosuppressive regimen.