D
Dimitris Georgellis
Researcher at National Autonomous University of Mexico
Publications - 59
Citations - 3919
Dimitris Georgellis is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Response regulator & Signal transduction. The author has an hindex of 30, co-authored 56 publications receiving 3624 citations. Previous affiliations of Dimitris Georgellis include Harvard University.
Papers
More filters
Journal ArticleDOI
Quinones as the Redox Signal for the Arc Two-Component System of Bacteria
TL;DR: It is shown that oxidized forms of quinone electron carriers act as direct negative signals that inhibit autophosphorylation of ArcB during aerobiosis, and provides a link between the electron transport chain and gene expression.
Journal ArticleDOI
A novel sRNA component of the carbon storage regulatory system of Escherichia coli.
Thomas Weilbacher,Kazushi Suzuki,Ashok Kumar Dubey,Xin Wang,Seshigirao Gudapaty,Igor Y. Morozov,Carol S. Baker,Dimitris Georgellis,Paul Babitzke,Tony Romeo +9 more
TL;DR: Small untranslated RNAs (sRNAs) perform a variety of important functions in bacteria, and the discovery of CsrC is intriguing, in that a similar sRNA, CsrB, performs essentially the same function.
Journal ArticleDOI
Identification of a quinone-sensitive redox switch in the ArcB sensor kinase
TL;DR: A pivotal link in the Arc signal transduction pathway connecting the redox state of the quinone pool to the transcriptional apparatus is elucidated and the molecular mechanism of kinase silencing involves the oxidation of two cytosol-located redox-active cysteine residues that participate in intermolecular disulfide bond formation.
Journal ArticleDOI
Regulatory Circuitry of the CsrA/CsrB and BarA/UvrY Systems of Escherichia coli
Kazushi Suzuki,Xin Wang,Thomas Weilbacher,Anna Karin Pernestig,Öjar Melefors,Dimitris Georgellis,Paul Babitzke,Tony Romeo +7 more
TL;DR: It is demonstrated that uvrY resides downstream from csrA in a signaling pathway for csrB and that CsrA stimulates UvrY-dependent activation of cSRB expression by BarA-dependent and -independent mechanisms.
Journal ArticleDOI
Circuitry linking the Csr and stringent response global regulatory systems
Adrianne N. Edwards,Laura M. Patterson-Fortin,Christopher A. Vakulskas,Jeffrey W. Mercante,Katarzyna Potrykus,Daniel Vinella,Martha I. Camacho,Joshua A. Fields,Stuart A. Thompson,Dimitris Georgellis,Michael Cashel,Paul Babitzke,Tony Romeo,Tony Romeo +13 more
TL;DR: It is proposed that the Csr system fine‐tunes the stringent response and discusses biological implications of the composite circuitry.