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Öjar Melefors
Researcher at Karolinska Institutet
Publications - 50
Citations - 2878
Öjar Melefors is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Gene & Ferritin. The author has an hindex of 30, co-authored 50 publications receiving 2735 citations. Previous affiliations of Öjar Melefors include Public Health Agency of Sweden & Umeå University.
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Journal ArticleDOI
Regulatory Circuitry of the CsrA/CsrB and BarA/UvrY Systems of Escherichia coli
Kazushi Suzuki,Xin Wang,Thomas Weilbacher,Anna Karin Pernestig,Öjar Melefors,Dimitris Georgellis,Paul Babitzke,Tony Romeo +7 more
TL;DR: It is demonstrated that uvrY resides downstream from csrA in a signaling pathway for csrB and that CsrA stimulates UvrY-dependent activation of cSRB expression by BarA-dependent and -independent mechanisms.
Journal ArticleDOI
Translational control of 5-aminolevulinate synthase mRNA by iron-responsive elements in erythroid cells.
Öjar Melefors,B Goossen,Hans E. Johansson,Renata Stripecke,Nicola K. Gray,Matthias W. Hentze +5 more
TL;DR: The iron-responsive element motif contained in eALAS mRNA is shown to be sufficient to confer translational control to a reporter mRNA both in transfected MEL cells and in vitro.
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Roles of curli, cellulose and BapA in Salmonella biofilm morphology studied by atomic force microscopy
Kristina Jonas,Kristina Jonas,Henrik Tomenius,Henrik Tomenius,Henrik Tomenius,Abdul Kader,Staffan Normark,Staffan Normark,Ute Römling,Lyubov Belova,Öjar Melefors,Öjar Melefors +11 more
TL;DR: This work demonstrates that atomic force microscopy can efficiently be used as a tool to monitor the morphology of bacteria grown as colonies on agar plates or within biofilms formed in a liquid at high resolution.
Journal ArticleDOI
Identification of UvrY as the Cognate Response Regulator for the BarA Sensor Kinase in Escherichia coli
TL;DR: The results provide the first biochemical evidence as well as genetic support for a link between BarA and UvrY, suggesting that the two proteins constitute a new two-component system for gene regulation in Escherichia coli.
Journal ArticleDOI
The RNA binding protein CsrA controls cyclic di-GMP metabolism by directly regulating the expression of GGDEF proteins.
Kristina Jonas,Kristina Jonas,Adrianne N. Edwards,Roger Simm,Tony Romeo,Tony Romeo,Ute Römling,Öjar Melefors,Öjar Melefors +8 more
TL;DR: Data demonstrate a global role for CsrA in the regulation of c‐di‐GMP metabolism by regulating the expression of GGDEF proteins at the post‐transcriptional level.