D
Dirk Heyken
Researcher at Humboldt University of Berlin
Publications - 1
Citations - 290
Dirk Heyken is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Protein subunit & Gene. The author has an hindex of 1, co-authored 1 publications receiving 274 citations.
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Inhibition of Proteasome Activity Induces Concerted Expression of Proteasome Genes and de Novo Formation of Mammalian Proteasomes
Silke Meiners,Dirk Heyken,Andrea Weller,Antje Ludwig,Karl Stangl,Peter-M. Kloetzel,Elke Krüger +6 more
TL;DR: The experiments present the first evidence that the amount of proteasomes in mammalia is regulated at the transcriptional level and that there exists an autoregulatory feedback mechanism that allows the compensation of reduced proteasome activity.