Diya Lv

TL;DR: A novel comparative normal/failing rat myocardium CMC analysis system based on online column selection and comprehensive two-dimensional chromatography/monolithic column/time-of-flight mass spectrometry was developed for parallel comparison of the chromatographic behaviors on both normal and pathological CMC columns, suitable for screening specific active components from herbal medicines by increasing the specificity of screened results.

TL;DR: The result demonstrated that the proposed comprehensive 2D HepG2/CMC/monolithic column/TOFMS system has the advantages of strong recognition and rapid analysis abilities for the total screening procedure, which will be selectable and practical in drug discovery from complex HM samples and can also be applied to other biochromatography models.

TL;DR: This study put forward for the first time a method which combined thin-layer chromatography (TLC) and surface-enhanced Raman scattering (SERS) to directly identify trace adulterant and it was found that the proposed method was simple, rapid, and accurate.

TL;DR: It is demonstrated that the cardiovascular protective effect of YXST mainly involved the immune and cardiovascular systems.

TL;DR: Systemically demonstrated the feasibility of SPR biosensor-based screening method applying to complex drug systems, and the findings suggest that SPR-AIRS could be a sensitive and effective solution for the discovery of active compounds from a complex matrix.