D
Dong-Ming Su
Researcher at University of North Texas Health Science Center
Publications - 58
Citations - 2775
Dong-Ming Su is an academic researcher from University of North Texas Health Science Center. The author has contributed to research in topics: Thymic involution & T cell. The author has an hindex of 25, co-authored 53 publications receiving 2342 citations. Previous affiliations of Dong-Ming Su include University of Texas at Tyler & University of Texas Health Science Center at Tyler.
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Journal ArticleDOI
Cross-talk between human neural stem/progenitor cells and peripheral blood mononuclear cells in an allogeneic co-culture model.
Hongxia Zhang,Bei Shao,Qichuan Zhuge,Peng Wang,Chengcai Zheng,Weilong Huang,Chenqi Yang,Brian Wang,Dong-Ming Su,Kunlin Jin,Kunlin Jin +10 more
TL;DR: The data suggest that hNSCs cross-talk with immune cells, and allogeneic peripheral blood mononuclear cells (PBMCs) significantly promote the proliferation and differentiation of hN SCs.
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Thymus Functionality Needs More Than a Few TECs
TL;DR: The contributions of the many stromal cell types participating in the formation, expansion, and contraction of the thymus under normal and pathophysiological processes are explored to better inform approaches for restoringThymus functionality when an individuals’ own tissue is congenitally, clinically, or accidentally rendered non-functional.
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MicroRNAs Regulate Thymic Epithelium in Age-Related Thymic Involution via Down- or Upregulation of Transcription Factors.
TL;DR: The current understanding and recent studies about how miRNAs are involved in age-related thymic involution via regulation of TEC-autonomous TFs are reviewed.
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Accumulation of pTreg cells is detrimental in late‐onset (aged) mouse model of multiple sclerosis
TL;DR: Evidence is provided and mechanism that accumulated aged pTreg cells play a detrimental role in neuronal inflammation of aged MS is provided, thereby ameliorating the disease in the aged EAE mice.
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A New Avenue to Cure Cancer by Turning Adaptive Immune T Cells to Innate Immune NK Cells via Reprogramming
TL;DR: This exciting finding represents a major breakthrough towards curing cancer and identifies an important, novel transcription factor in the thymus development.