D
Dong Yeon Shin
Researcher at Gwangju Institute of Science and Technology
Publications - 3
Citations - 85
Dong Yeon Shin is an academic researcher from Gwangju Institute of Science and Technology. The author has contributed to research in topics: Ubiquitin & Proteasome. The author has an hindex of 3, co-authored 3 publications receiving 83 citations.
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Production of recombinant amyloid-β peptide 42 as an ubiquitin extension
TL;DR: The recombinant Abeta42 prepared in this study has the same toxic effect on human neuroblastoma SH-SY5Y cells comparing with chemically synthesized, commercial one, indicating this ubiquitin fusion technique is an attractive method for production of aggregation-prone peptides such as Abeta 42.
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Cytosolic amyloid-β peptide 42 escaping from degradation induces cell death
TL;DR: This study ectopically expressed Abeta42 in the cytoplasm of SH-SY5Y neuroblastoma cells by expressing a fusion protein of GFP-tagged ubiquitin and Abeta 42 (GFPUb-Abeta42).
Journal ArticleDOI
The ubiquitin-interacting motifs of S5a as a unique upstream inhibitor of the 26S proteasome
TL;DR: A potential role of S5a-UIMs as an upstream proteasomal inhibitor is suggested by blocking the subset of substrates from delivery to the 26S proteasome.