Dongmei Jiang

TL;DR: In this paper, the authors show that Betaine can improve obesity and associated MS via the gut microbiota-derived miR-378a/YY1 regulatory axis, and reveal a novel mechanism by which gut microbiota improve host health.

TL;DR: It is demonstrated that miR-204-5p inhibits myoblast differentiation by targeting MEF2C and ERRγ, a potential regulator that could influence myogenesis.

TL;DR: Results demonstrated that tRFs are involved in regulating the response of myocardial hypertrophy, and might serve as novel epigenetic factors that contribute to the intergenerational inheritance of cardiachypertrophy.

TL;DR: It is shown that miR-125a-5p was expressed at lower levels in the adipose tissues of high-fat diet (HFD)fed mice than the normal chow (NCW)-fed mice, and analysis confirmed that the process of miR -125a -5p inhibiting 3T3-L1 preadipocyte differentiation might be associated with the regulation of fatty acid metabolism related genes.

TL;DR: Results imply that tRFGluTTC may act as a novel epigenetic molecule regulating adipogenesis and could provide a new strategy for the intervention treatment of obesity.