Showing papers by "Dorothea Fiedler published in 2011"
TL;DR: A novel technique for administering focal fractionated irradiation will facilitate mechanistic and translational studies of SMNs and reveal discrete patterns of somatic Nf1 and Trp53 inactivation and hyperactive Ras signaling in many radiation-induced solid tumors.
Abstract: Findings offer the first validated mouse model to study secondary malignancies, an increasingly common complication of cancer therapy in survivors that has yet to be systematically analyzed.
27 citations