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Bruce A. Faddegon
Researcher at University of California, San Francisco
Publications - 133
Citations - 6070
Bruce A. Faddegon is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Monte Carlo method & Beam (structure). The author has an hindex of 31, co-authored 128 publications receiving 5206 citations. Previous affiliations of Bruce A. Faddegon include Harvard University & Fox Chase Cancer Center.
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BEAM: a Monte Carlo code to simulate radiotherapy treatment units.
TL;DR: BEAM, a general purpose Monte Carlo code to simulate the radiation beams from radiotherapy units including high-energy electron and photon beams, 60Co beams and orthovoltage units, is described.
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TOPAS: An innovative proton Monte Carlo platform for research and clinical applications
TL;DR: An innovative proton Monte Carlo platform is developed and a custom-designed TOPAS parameter control system was placed at the heart of the code to meet requirements for ease of use, reliability, and repeatability without sacrificing flexibility.
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Report of the AAPM Task Group No. 105 : Issues associated with clinical implementation of Monte Carlo-based photon and electron external beam treatment planning
Indrin J. Chetty,Bruce Curran,Joanna E. Cygler,John J. DeMarco,Gary A. Ezzell,Bruce A. Faddegon,Iwan Kawrakow,Paul J. Keall,Helen Liu,Charlie Ma,David W. O. Rogers,Jan Seuntjens,Daryoush Sheikh-Bagheri,Jeffrey V. Siebers +13 more
TL;DR: The purpose of this report is to set out the salient issues associated with clinical implementation and experimental verification of MC dose algorithms, and to provide the framework upon which to build a comprehensive program for commissioning and routine quality assurance of MC-based treatment planning systems.
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Description and dosimetric verification of the PEREGRINE Monte Carlo dose calculation system for photon beams incident on a water phantom.
C. L. Hartmann Siantar,R. S. Walling,T. P. Daly,Bruce A. Faddegon,N. Albright,Paul M. Bergstrom,Alex F. Bielajew,Cynthia H. Chuang,D. Garrett,R. K. House,D K Knapp,D. J. Wieczorek,Lynn J. Verhey +12 more
TL;DR: The implementation and overall dosimetric accuracy of PEREGRINE physics algorithms, beam model, and beam commissioning procedure are described and calculations with measurements in a water phantom for open fields, wedges, blocks, and a multileaf collimator are compared.
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TH2-Polarized CD4+ T Cells and Macrophages Limit Efficacy of Radiotherapy
Stephen L. Shiao,Brian Ruffell,David G. DeNardo,Bruce A. Faddegon,Catherine C. Park,Lisa M. Coussens +5 more
TL;DR: It is shown that clinical responses to cytotoxic therapy in general can be improved by neutralizing dominant TH2-based programs driving protumorigenic and immune-suppressive pathways in mammary (breast) tumors to improve outcomes.