D
Doug Thrower
Publications - 1
Citations - 1066
Doug Thrower is an academic researcher. The author has contributed to research in topics: Vinblastine & Spindle apparatus. The author has an hindex of 1, co-authored 1 publications receiving 1023 citations.
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Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations.
TL;DR: The results indicate that taxol shares a common antiproliferative mechanism with vinblastine, and at its lowest effective concentrations, taxol appears to block mitosis by kinetically stabilizing spindle microtubules and not by changing the mass of polymerizedmicrotubules.