Douglas W. Selinger

TL;DR: A high-resolution “genome array” for the study of gene expression and regulation in Escherichia coli detected transcripts for 97% and 87% of the ORFs in stationary and log phases, and transcription of between 3,000 and 4,000 predicted ORFs was observed from the antisense strand, indicating that most of the genome is transcribed at a detectable level.

TL;DR: Subgenic-resolution oligonucleotide microarrays were used to study global RNA degradation in wild-type Escherichia coli MG1655 and found a weak but highly significant correlation between the degradation of adjacent operon regions, suggesting that stability is determined by a combination of local and operon-wide stability determinants.

TL;DR: Using a microarray-based approach, supercoiling-dependent gene transcription is characterized by expression profiling under conditions of high salt, in conjunction with the microbial antibiotics novobiocin, pefloxacin, and chloramphenicol and supports regulation by the global stress sigma factor rpoS.

TL;DR: It is demonstrated that monoubiquitinated SMad6 impairs the binding affinity of non‐modified SMAD6 to the BMP type I receptor and UBE2O andSMAD6 cooperated in the regulation of BMP7‐induced adipogenesis.

TL;DR: The immunoglobulin alpha (IGHAC) and epsilon (IGHEC) germline constant region genes were isolated from a dog liver genomic DNA library and the complete exon/intron sequence of these genes is described.