F
Frederick R. Blattner
Researcher at University of Wisconsin-Madison
Publications - 215
Citations - 38502
Frederick R. Blattner is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 83, co-authored 215 publications receiving 36605 citations. Previous affiliations of Frederick R. Blattner include Wisconsin Alumni Research Foundation & University of California, San Diego.
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Journal ArticleDOI
The Complete Genome Sequence of Escherichia coli K-12
Frederick R. Blattner,Guy Plunkett,Craig A. Bloch,Nicole T. Perna,Valerie Burland,Monica Riley,Julio Collado-Vides,Jeremy D. Glasner,Christopher K. Rode,George F. Mayhew,Jason Gregor,Nelson Wayne Davis,Heather A. Kirkpatrick,Michael A. Goeden,Debra J. Rose,Bob Mau,Ying Shao +16 more
TL;DR: The 4,639,221-base pair sequence of Escherichia coli K-12 is presented and reveals ubiquitous as well as narrowly distributed gene families; many families of similar genes within E. coli are also evident.
Journal ArticleDOI
Mauve: multiple alignment of conserved genomic sequence with rearrangements.
TL;DR: This work presents methods for identification and alignment of conserved genomic DNA in the presence of rearrangements and horizontal transfer and evaluated the quality of Mauve alignments and drawn comparison to other methods through extensive simulations of genome evolution.
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Genome sequence of enterohaemorrhagic Escherichia coli O157:H7
Nicole T. Perna,Guy Plunkett,Valerie Burland,Bob Mau,Jeremy D. Glasner,Debra J. Rose,George F. Mayhew,Peter Evans,Jason Gregor,Heather A. Kirkpatrick,György Pósfai,Jeremiah D. Hackett,Sara A. Klink,Adam T. Boutin,Ying Shao,Leslie Miller,Erik J. Grotbeck,N. Wayne Davis,Alex Lim,Eileen T. Dimalanta,Konstantinos Potamousis,Jennifer Apodaca,Thomas Anantharaman,Jieyi Lin,Galex Yen,David C. Schwartz,Rodney A. Welch,Frederick R. Blattner +27 more
TL;DR: It is found that lateral gene transfer is far more extensive than previously anticipated and 1,387 new genes encoded in strain-specific clusters of diverse sizes were found in O157:H7, including candidate virulence factors, alternative metabolic capacities, several prophages and other new functions—all of which could be targets for surveillance.
Journal ArticleDOI
Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli
Rodney A. Welch,Valerie Burland,Guy Plunkett,Peter Redford,Paula L. Roesch,David A. Rasko,Eric L. Buckles,S. R. Liou,S. R. Liou,Adam T. Boutin,Adam T. Boutin,Jeremiah D. Hackett,Jeremiah D. Hackett,D. Stroud,George F. Mayhew,Debra J. Rose,Shiguo Zhou,David C. Schwartz,Nicole T. Perna,Harry L. T. Mobley,Michael S. Donnenberg,Frederick R. Blattner +21 more
TL;DR: The complete genome sequence of uropathogenic Escherichia coli, strain CFT073 is presented and Comparisons indicate that extraintestinal pathogenic E. coli arose independently from multiple clonal lineages.
Journal ArticleDOI
Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array.
Sangeet Singh-Gasson,Roland Green,Yongjian Yue,Clark J. Nelson,Frederick R. Blattner,Michael R. Sussman,Franco Cerrina +6 more
TL;DR: A maskless array synthesizer (MAS) that replaces the chrome masks with virtual masks generated on a computer, which are relayed to a digital micromirror array to grow desired oligonucleotides in a selected pattern.