Dragic Vukomanovic

TL;DR: In this article, a sensitive voltammetric stripping procedure for trace measurement of chromium (VI) and (III) in aqueous samples is reported, based on the preconcentration of a chromium(VI)−pyrocatechol violet complex at HMDE from an acetate buffered solution.

TL;DR: Using X-ray crystallography, the structures of several complexes of HO-1 with novel inhibitors have been elucidated, which provided insightful information regarding the salient features required for inhibitor binding, including the structural basis for non-competitive inhibition, flexibility and adaptability of the inhibitor binding pocket, and multiple, potential interaction subsites, all of which can be exploited in future drug-design strategies.

TL;DR: The replacement of imidazole by other azoles led to the discovery of novel 1H‐1,2,4‐triazole‐ and1H‐tetrazole‐based inhibitors equipotent to a leadImidazoles‐based inhibitor, which proved to be detrimental to the inhibition of HO, with a few exceptions.

TL;DR: An adsorptive stripping voltammetric (AdSV) method that can be used for analysis of pyocyanin at the nanomolar level is developed and tested for utility in Mueller-Hinton broth diluted from 20 to 200 times in a 10-mM ammonia buffer.

TL;DR: A series of inhibition candidates containing a shorter linkage of an azole, usually an imidazole, and an aromatic moiety based on inhibition of heme oxygenases are designed and synthesized for potentially useful pharmacological and therapeutic applications.