Duangjai Sahassananda

TL;DR: Plasma PfHRP2 concentrations may be used to estimate the total body parasite biomass in acute falciparum malaria, and suggested that admission to hospital with uncomplicated malaria often follows schizogony—but in severe malaria is unrelated to stage of parasite development.

TL;DR: An assessment of the stage-dependent release of PfHRP2 is an essential prerequisite for future studies aimed at estimating the total patient parasite mass from the peripheral blood Pf HRP2 concentration.

TL;DR: It is suggested that measurement of PfHRP2 in plasma could provide an alternative approach to the assessment of the parasite biomass, and thus prognosis, in severe malaria, and that this could be done simply by using the currently available dipsticks.

TL;DR: The accuracy of IgM ELISA is limited in the setting, and a receiver operating characteristic curve was used to determine the optimal cutoff value.

TL;DR: This study identified several clinical factors independently associated with the development of severe d Dengue among hospitalized adults with dengue that can aid in the early recognition and prompt management of at-risk patients to reduce morbidity and mortality.