N
Nicholas P. J. Day
Researcher at University of Oxford
Publications - 752
Citations - 59289
Nicholas P. J. Day is an academic researcher from University of Oxford. The author has contributed to research in topics: Malaria & Population. The author has an hindex of 102, co-authored 708 publications receiving 50588 citations. Previous affiliations of Nicholas P. J. Day include Wellcome Trust & John Radcliffe Hospital.
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Journal ArticleDOI
Artemisinin Resistance in Plasmodium falciparum Malaria
Arjen M. Dondorp,François Nosten,Poravuth Yi,Debashish Das,Aung Phae Phyo,Joel Tarning,Khin Maung Lwin,Frédéric Ariey,Warunee Hanpithakpong,Sue J. Lee,Pascal Ringwald,Kamolrat Silamut,Mallika Imwong,Kesinee Chotivanich,Pharath Lim,Trent Herdman,Sen Sam An,Shunmay Yeung,Pratap Singhasivanon,Nicholas P. J. Day,Niklas Lindegardh,Duong Socheat,Nicholas J. White +22 more
TL;DR: The overall median clearance times were 84 hours (interquartile range, 60 to 96) in Pailin and 48 hours in Wang Pha (P<0.001) in each of the two locations as discussed by the authors.
Journal ArticleDOI
Multilocus sequence typing for characterization of methicillin-resistant and methicillin-susceptible clones of Staphylococcus aureus.
Mark C. Enright,Nicholas P. J. Day,Catrin E. Davies,Sharon J Peacock,Sharon J Peacock,Brian G. Spratt +5 more
TL;DR: A multilocus sequence typing (MLST) scheme has been developed for Staphylococcus aureus and provides an unambiguous method for assigning MRSA and MSSA isolates to known clones or assigning them as novel clones via the Internet.
Journal ArticleDOI
Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis
Christopher J L Murray,Kevin S Ikuta,Fablina Sharara,Lucien Swetschinski,Gisela Robles Aguilar,Authia Gray,Chieh Fei Han,Catherine Bisignano,Puja C Rao,Eve E. Wool,Sarah Charlotte Johnson,Annie J. Browne,Michael G. Chipeta,Frederick Fell,Sean Hackett,Georgina Haines-Woodhouse,Bahar H. Kashef Hamadani,Emmanuelle A. P. Kumaran,Barney McManigal,Sureeruk Achalapong,Ramesh Agarwal,Samuel Akech,Samuel B. Albertson,John H Amuasi,Jason R. Andrews,Aleskandr Aravkin,Elizabeth A. Ashley,François-Xavier Babin,Freddie Bailey,Stephen Baker,Buddha Basnyat,Adrie Bekker,Rose G Bender,James A. Berkley,Adhisivam Bethou,Julia Bielicki,Suppawat Boonkasidecha,James Bukosia,Cristina Gardony Carvalheiro,Carlos A Castañeda-Orjuela,Vilada Chansamouth,Suman Chaurasia,Sara Chiurchiù,Fazle Rabbi Chowdhury,Rafai Clotaire Donatien,Aislinn Cook,Ben S. Cooper,Tim R. Cressey,Elia Criollo-Mora,Matthew Cunningham,Saffiatou Darboe,Nicholas P. J. Day,Maia De Luca,Klara Dokova,Angela Dramowski,Susanna Dunachie,Thuy Duong Bich,Tim Eckmanns,Daniel Eibach,Amir Emami,Nicholas A. Feasey,Natasha Fisher-Pearson,Karen Forrest,Coralith Garcia,Denise O Garrett,Petra Gastmeier,Ababi Zergaw Giref,Rachel C Greer,Vikas Gupta,Sebastian Haller,Andrea Haselbeck,Simon I. Hay,M. Holm,Susan Hopkins,Yingfen Hsia,Kenneth Iregbu,Jan Jacobs,Daniel Jarovsky,Fatemeh Javanmardi,Adam Jenney,Meera Khorana,Suwimon Khusuwan,Niranjan Kissoon,Elsa Kobeissi,Tomislav Kostyanev,Fiorella Krapp,Ralf Krumkamp,Ajay Kumar,Hmwe H Kyu,Cherry Lim,Kruy Lim,Direk Limmathurotsakul,Michael J. Loftus,Miles Lunn,Jianing Ma,Anand Manoharan,Florian Marks,Jürgen May,Mayfong Mayxay,Neema Mturi,Tatiana Múnera-Huertas,Patrick Musicha,Lilian Musila,Marisa Márcia Mussi-Pinhata,Ravi Naidu,Tomoka Nakamura,Ruchi Nanavati,Sushma Nangia,Paul N. Newton,Chanpheaktra Ngoun,Amanda Novotney,Davis Nwakanma,Christina W. Obiero,Theresa J. Ochoa,Antonio Olivas-Martinez,Piero Olliaro,Edna Ooko,Edgar Ortiz-Brizuela,Pradthana Ounchanum,Gi Deok Pak,Jose Luis Paredes,Anton Y. Peleg,Carlo Perrone,Thong Phe,Koukeo Phommasone,Nishad Plakkal,Alfredo Ponce-de-León,Mathieu Raad,Tanusha Ramdin,Sayaphet Rattanavong,Amy Riddell,Tamalee Roberts,Julie V. Robotham,Anna Roca,Victor D. Rosenthal,Kristina E. Rudd,Neal Russell,Helio S. Sader,Weerawut Saengchan,Janice W. Schnall,John Anthony G Scott,Samroeng Seekaew,Mike Sharland,Madhusudhan Shivamallappa,José Sifuentes-Osornio,A. John Simpson,Nicolas Steenkeste,Andrew J. Stewardson,Temenuga Stoeva,Nidanuch Tasak,Areerat Thaiprakong,Guy E. Thwaites,Caroline Tigoi,Claudia Turner,Paul Turner,H. Rogier van Doorn,Sithembiso Velaphi,Avina Vongpradith,Manivanh Vongsouvath,Huong X. Vu,Timothy R. Walsh,Judd L. Walson,Seymour Waner,Tri Wangrangsimakul,Prapass Wannapinij,Teresa M. Wozniak,Tracey E M W Young Sharma,Kalvin C. Yu,Peng Zheng,Benn Sartorius,Alan D. Lopez,Andy Stergachis,Catrin E. Moore,Christiane Dolecek,Mohsen Naghavi +174 more
TL;DR: This study provides the first comprehensive assessment of the global burden of AMR, as well as an evaluation of the availability of data, and estimates aggregated to the global and regional level.
Journal ArticleDOI
Spread of Artemisinin Resistance in Plasmodium falciparum Malaria
Elizabeth A. Ashley,Mehul Dhorda,Rick M. Fairhurst,Chanaki Amaratunga,Pharath Lim,Seila Suon,Sokunthea Sreng,Jennifer M. Anderson,Mao S,Sam B,Chantha Sopha,Char Meng Chuor,Chea Nguon,Siv Sovannaroth,Sasithon Pukrittayakamee,Podjanee Jittamala,Kesinee Chotivanich,K Chutasmit,C Suchatsoonthorn,R Runcharoen,Tran Tinh Hien,Nguyen Thuy-Nhien,Thanh Nv,Nguyen Hoan Phu,Ye Htut,Han Kt,Kyin Hla Aye,Olugbenga A. Mokuolu,Rasaq Olaosebikan,Olaleke Oluwasegun Folaranmi,Mayfong Mayxay,Maniphone Khanthavong,Bouasy Hongvanthong,Paul N. Newton,M A Onyamboko,Caterina I. Fanello,Antoinette Tshefu,Neelima Mishra,Neena Valecha,Aung Pyae Phyo,François Nosten,Yi P,Rupam Tripura,Steffen Borrmann,Mahfudh Bashraheil,Judy Peshu,M A Faiz,Aniruddha Ghose,M A Hossain,Rasheda Samad,M. R. Rahman,Manal Hasan,Ashraful Islam,Olivo Miotto,Roberto Amato,Bronwyn MacInnis,Jim Stalker,Dominic P. Kwiatkowski,Zbynek Bozdech,Atthanee Jeeyapant,Phaik Yeong Cheah,Tharisara Sakulthaew,Jeremy Chalk,Benjamas Intharabut,Kamolrat Silamut,Lee Sj,Benchawan Vihokhern,Chanon Kunasol,Mallika Imwong,Joel Tarning,Taylor Wj,Shunmay Yeung,Charles J. Woodrow,Jennifer A. Flegg,Debashish Das,Jennifer L. Smith,Meera Venkatesan,Christopher V. Plowe,Kasia Stepniewska,Philippe J Guerin,Arjen M. Dondorp,Nicholas P. J. Day,Nicholas J. White +82 more
TL;DR: Prolonged courses of artemisinin-based combination therapies are currently efficacious in areas where standard 3-day treatments are failing, and the incidence of pretreatment and post-treatment gametocytemia was higher among patients with slow parasite clearance, suggesting greater potential for transmission.
Journal ArticleDOI
Evolution of MRSA During Hospital Transmission and Intercontinental Spread
Simon R. Harris,Edward J. Feil,Matthew T. G. Holden,Michael A. Quail,Emma K. Nickerson,Emma K. Nickerson,Narisara Chantratita,Susana Gardete,Susana Gardete,Ana Tavares,Nicholas P. J. Day,Nicholas P. J. Day,Jodi A. Lindsay,Jonathan D. Edgeworth,Jonathan D. Edgeworth,Hermínia de Lencastre,Hermínia de Lencastre,Julian Parkhill,Sharon J. Peacock,Sharon J. Peacock,Stephen D. Bentley +20 more
TL;DR: A high-throughput genomics approach is used to show that isolates of methicillin-resistant Staphylococcus aureus are precisely differentiated into a global geographic structure and suggest that intercontinental transmission has occurred for nearly four decades.